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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SLIT1_HUMAN (O75093)

Summary

This is the summary of UniProt entry SLIT1_HUMAN (O75093).

Description: Slit homolog 1 protein
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 1534 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 33
low_complexity n/a 17 32
Pfam LRRNT 33 60
Pfam LRR_8 61 121
Pfam LRR_8 109 169
low_complexity n/a 109 118
Pfam LRR_8 157 217
low_complexity n/a 185 195
Pfam LRRCT 239 264
Pfam LRRNT 281 308
Pfam LRR_8 309 369
Pfam LRR_8 357 413
low_complexity n/a 379 387
Pfam LRR_8 381 441
Pfam LRRCT 463 488
Pfam LRRNT 512 539
Pfam LRR_8 589 649
Pfam LRR_8 613 673
Pfam LRRCT 695 720
Pfam LRRNT 733 760
Pfam LRR_8 761 820
low_complexity n/a 791 807
Pfam LRR_8 808 868
low_complexity n/a 830 838
Pfam LRRCT 890 915
Pfam EGF 929 960
Pfam EGF 968 1001
Pfam EGF 1009 1039
Pfam EGF 1047 1079
Pfam EGF 1087 1117
Pfam hEGF 1136 1157
Pfam Laminin_G_2 1194 1322
Pfam hEGF 1347 1368

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O75093. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MALTPGWGSS AGPVRPELWL LLWAAAWRLG ASACPALCTC TGTTVDCHGT
50
51
GLQAIPKNIP RNTERLELNG NNITRIHKND FAGLKQLRVL QLMENQIGAV
100
101
ERGAFDDMKE LERLRLNRNQ LHMLPELLFQ NNQALSRLDL SENAIQAIPR
150
151
KAFRGATDLK NLQLDKNQIS CIEEGAFRAL RGLEVLTLNN NNITTIPVSS
200
201
FNHMPKLRTF RLHSNHLFCD CHLAWLSQWL RQRPTIGLFT QCSGPASLRG
250
251
LNVAEVQKSE FSCSGQGEAG RVPTCTLSSG SCPAMCTCSN GIVDCRGKGL
300
301
TAIPANLPET MTEIRLELNG IKSIPPGAFS PYRKLRRIDL SNNQIAEIAP
350
351
DAFQGLRSLN SLVLYGNKIT DLPRGVFGGL YTLQLLLLNA NKINCIRPDA
400
401
FQDLQNLSLL SLYDNKIQSL AKGTFTSLRA IQTLHLAQNP FICDCNLKWL
450
451
ADFLRTNPIE TSGARCASPR RLANKRIGQI KSKKFRCSAK EQYFIPGTED
500
501
YQLNSECNSD VVCPHKCRCE ANVVECSSLK LTKIPERIPQ STAELRLNNN
550
551
EISILEATGM FKKLTHLKKI NLSNNKVSEI EDGAFEGAAS VSELHLTANQ
600
601
LESIRSGMFR GLDGLRTLML RNNRISCIHN DSFTGLRNVR LLSLYDNQIT
650
651
TVSPGAFDTL QSLSTLNLLA NPFNCNCQLA WLGGWLRKRK IVTGNPRCQN
700
701
PDFLRQIPLQ DVAFPDFRCE EGQEEGGCLP RPQCPQECAC LDTVVRCSNK
750
751
HLRALPKGIP KNVTELYLDG NQFTLVPGQL STFKYLQLVD LSNNKISSLS
800
801
NSSFTNMSQL TTLILSYNAL QCIPPLAFQG LRSLRLLSLH GNDISTLQEG
850
851
IFADVTSLSH LAIGANPLYC DCHLRWLSSW VKTGYKEPGI ARCAGPQDME
900
901
GKLLLTTPAK KFECQGPPTL AVQAKCDLCL SSPCQNQGTC HNDPLEVYRC
950
951
ACPSGYKGRD CEVSLDSCSS GPCENGGTCH AQEGEDAPFT CSCPTGFEGP
1000
1001
TCGVNTDDCV DHACANGGVC VDGVGNYTCQ CPLQYEGKAC EQLVDLCSPD
1050
1051
LNPCQHEAQC VGTPDGPRCE CMPGYAGDNC SENQDDCRDH RCQNGAQCMD
1100
1101
EVNSYSCLCA EGYSGQLCEI PPHLPAPKSP CEGTECQNGA NCVDQGNRPV
1150
1151
CQCLPGFGGP ECEKLLSVNF VDRDTYLQFT DLQNWPRANI TLQVSTAEDN
1200
1201
GILLYNGDND HIAVELYQGH VRVSYDPGSY PSSAIYSAET INDGQFHTVE
1250
1251
LVAFDQMVNL SIDGGSPMTM DNFGKHYTLN SEAPLYVGGM PVDVNSAAFR
1300
1301
LWQILNGTGF HGCIRNLYIN NELQDFTKTQ MKPGVVPGCE PCRKLYCLHG
1350
1351
ICQPNATPGP MCHCEAGWVG LHCDQPADGP CHGHKCVHGQ CVPLDALSYS
1400
1401
CQCQDGYSGA LCNQAGALAE PCRGLQCLHG HCQASGTKGA HCVCDPGFSG
1450
1451
ELCEQESECR GDPVRDFHQV QRGYAICQTT RPLSWVECRG SCPGQGCCQG
1500
1501
LRLKRRKFTF ECSDGTSFAE EVEKPTKCGC ALCA                 
1534
 

Show the unformatted sequence.

Checksums:
CRC64:47B11CE6704A3E1D
MD5:3bbd1b76c863cf770b7c6f607741d286

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.