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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: AT2C2_HUMAN (O75185)

Summary

This is the summary of UniProt entry AT2C2_HUMAN (O75185).

Description: Calcium-transporting ATPase type 2C member 2 EC=3.6.3.8
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 946 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
coiled_coil n/a 26 46
Pfam Cation_ATPase_N 58 125
transmembrane n/a 110 128
low_complexity n/a 113 126
low_complexity n/a 133 147
transmembrane n/a 134 150
Pfam E1-E2_ATPase 164 357
disorder n/a 224 233
disorder n/a 285 288
transmembrane n/a 298 317
transmembrane n/a 323 352
Pfam Hydrolase 373 686
low_complexity n/a 736 750
Pfam Cation_ATPase_C 756 929
disorder n/a 782 783
transmembrane n/a 805 825
low_complexity n/a 834 848
transmembrane n/a 837 855
transmembrane n/a 875 892
low_complexity n/a 903 915
transmembrane n/a 904 922

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O75185. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVEGRVSEFL KKLGFSGGGR QYQALEKDEE EALIDEQSEL KAIEKEKKVT
50
51
ALPPKEACKC QKEDLARAFC VDLHTGLSEF SVTQRRLAHG WNEFVADNSE
100
101
PVWKKYLDQF KNPLILLLLG SALVSVLTKE YEDAVSIATA VLVVVTVAFI
150
151
QEYRSEKSLE ELTKMVPPEC NCLREGKLQH LLARELVPGD VVSLSIGDRI
200
201
PADIRLTEVT DLLVDESSFT GEAEPCSKTD SPLTGGGDLT TLSNIVFMGT
250
251
LVQYGRGQGV VIGTGESSQF GEVFKMMQAE ETPKTPLQKS MDRLGKQLTL
300
301
FSFGIIGLIM LIGWSQGKQL LSMFTIGVSL AVAAIPEGLP IVVMVTLVLG
350
351
VLRMAKKRVI VKKLPIVETL GCCSVLCSDK TGTLTANEMT VTQLVTSDGL
400
401
RAEVSGVGYD GQGTVCLLPS KEVIKEFSNV SVGKLVEAGC VANNAVIRKN
450
451
AVMGQPTEGA LMALAMKMDL SDIKNSYIRK KEIPFSSEQK WMAVKCSLKT
500
501
EDQEDIYFMK GALEEVIRYC TMYNNGGIPL PLTPQQRSFC LQEEKRMGSL
550
551
GLRVLALASG PELGRLTFLG LVGIIDPPRV GVKEAVQVLS ESGVSVKMIT
600
601
GDALETALAI GRNIGLCNGK LQAMSGEEVD SVEKGELADR VGKVSVFFRT
650
651
SPKHKLKIIK ALQESGAIVA MTGDGVNDAV ALKSADIGIA MGQTGTDVSK
700
701
EAANMILVDD DFSAIMNAVE EGKGIFYNIK NFVRFQLSTS ISALSLITLS
750
751
TVFNLPSPLN AMQILWINII MDGPPAQSLG VEPVDKDAFR QPPRSVRDTI
800
801
LSRALILKIL MSAAIIISGT LFIFWKEMPE DRASTPRTTT MTFTCFVFFD
850
851
LFNALTCRSQ TKLIFEIGFL RNHMFLYSVL GSILGQLAVI YIPPLQRVFQ
900
901
TENLGALDLL FLTGLASSVF ILSELLKLCE KYCCSPKRVQ MHPEDV    
946
 

Show the unformatted sequence.

Checksums:
CRC64:AEB061210ED09D1C
MD5:985b1e55c4c48bf9736e05c84ee6e6bf

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.