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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CXB3_HUMAN (O75712)

Summary

This is the summary of UniProt entry CXB3_HUMAN (O75712).

Description: Gap junction beta-3 protein
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 270 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Connexin 2 211
transmembrane n/a 20 39
low_complexity n/a 26 37
transmembrane n/a 77 97
low_complexity n/a 97 105
transmembrane n/a 128 149
low_complexity n/a 131 148
transmembrane n/a 186 211
low_complexity n/a 222 240
disorder n/a 257 258
disorder n/a 262 263

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O75712. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDWKTLQALL SGVNKYSTAF GRIWLSVVFV FRVLVYVVAA ERVWGDEQKD
50
51
FDCNTKQPGC TNVCYDNYFP ISNIRLWALQ LIFVTCPSLL VILHVAYREE
100
101
RERRHRQKHG DQCAKLYDNA GKKHGGLWWT YLFSLIFKLI IEFLFLYLLH
150
151
TLWHGFNMPR LVQCANVAPC PNIVDCYIAR PTEKKIFTYF MVGASAVCIV
200
201
LTICELCYLI CHRVLRGLHK DKPRGGCSPS SSASRASTCR CHHKLVEAGE
250
251
VDPDPGNNKL QASAPNLTPI                                 
270
 

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Checksums:
CRC64:E46D36E5835646A4
MD5:e62c00541c71e0aadcb505d56a3f92e6

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.