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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: JTB_HUMAN (O76095)

Summary

This is the summary of UniProt entry JTB_HUMAN (O76095).

Description: Protein JTB
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 146 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 30
Pfam JTB 37 143
transmembrane n/a 105 126

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O76095. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLAGAGRPGL PQGRHLCWLL CAFTLKLCQA EAPVQEEKLS ASTSNLPCWL
50
51
VEEFVVAEEC SPCSNFRAKT TPECGPTGYV EKITCSSSKR NEFKSCRSAL
100
101
MEQRLFWKFE GAVVCVALIF ACLVIIRQRQ LDRKALEKVR KQIESI    
146
 

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Checksums:
CRC64:CA7080543591C319
MD5:901cde6473059a924dbaaf97a3ae7e81

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
JTB 47 - 104 2KJX A 8 - 65 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.