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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TMCC1_HUMAN (O94876)

Summary

This is the summary of UniProt entry TMCC1_HUMAN (O94876).

Description: Transmembrane and coiled-coil domains protein 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 653 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 170
low_complexity n/a 152 166
low_complexity n/a 171 181
disorder n/a 184 236
Pfam Tmemb_cc2 231 640
coiled_coil n/a 234 254
disorder n/a 261 263
disorder n/a 276 280
disorder n/a 292 294
coiled_coil n/a 292 312
disorder n/a 304 327
disorder n/a 386 395
disorder n/a 404 405
disorder n/a 418 431
disorder n/a 434 440
disorder n/a 442 447
coiled_coil n/a 459 486
disorder n/a 474 475
disorder n/a 477 481
coiled_coil n/a 498 536
coiled_coil n/a 545 565
low_complexity n/a 564 572
transmembrane n/a 589 612
low_complexity n/a 592 603
transmembrane n/a 624 645

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O94876. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEPSGSEQLF EDPDPGGKSQ DAEARKQTES EQKLSKMTHN ALENINVIGQ
50
51
GLKHLFQHQR RRSSVSPHDV QQIQADPEPE MDLESQNACA EIDGVPTHPT
100
101
ALNRVLQQIR VPPKMKRGTS LHSRRGKPEA PKGSPQINRK SGQEMTAVMQ
150
151
SGRPRSSSTT DAPTSSAMME IACAAAAAAA ACLPGEEGTA ERIERLEVSS
200
201
LAQTSSAVAS STDGSIHTDS VDGTPDPQRT KAAIAHLQQK ILKLTEQIKI
250
251
AQTARDDNVA EYLKLANSAD KQQAARIKQV FEKKNQKSAQ TILQLQKKLE
300
301
HYHRKLREVE QNGIPRQPKD VFRDMHQGLK DVGAKVTGFS EGVVDSVKGG
350
351
FSSFSQATHS AAGAVVSKPR EIASLIRNKF GSADNIPNLK DSLEEGQVDD
400
401
AGKALGVISN FQSSPKYGSE EDCSSATSGS VGANSTTGGI AVGASSSKTN
450
451
TLDMQSSGFD ALLHEIQEIR ETQARLEESF ETLKEHYQRD YSLIMQTLQE
500
501
ERYRCERLEE QLNDLTELHQ NEILNLKQEL ASMEEKIAYQ SYERARDIQE
550
551
ALEACQTRIS KMELQQQQQQ VVQLEGLENA TARNLLGKLI NILLAVMAVL
600
601
LVFVSTVANC VVPLMKTRNR TFSTLFLVVF IAFLWKHWDA LFSYVERFFS
650
651
SPR                                                   
653
 

Show the unformatted sequence.

Checksums:
CRC64:B9C3A26AE9583FF2
MD5:9516868284fc5f7fcf191dab73e9bd72

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.