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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: LETM1_HUMAN (O95202)

Summary

This is the summary of UniProt entry LETM1_HUMAN (O95202).

Description: Mitochondrial proton/calcium exchanger protein {ECO:0000305}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 739 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
low_complexity n/a 9 29
disorder n/a 19 26
disorder n/a 28 29
low_complexity n/a 120 135
Pfam LETM1 153 418
low_complexity n/a 205 226
transmembrane n/a 206 229
low_complexity n/a 244 259
low_complexity n/a 441 459
disorder n/a 456 458
disorder n/a 461 540
coiled_coil n/a 463 483
low_complexity n/a 531 547
coiled_coil n/a 538 596
disorder n/a 546 548
low_complexity n/a 552 573
disorder n/a 556 560
disorder n/a 563 575
disorder n/a 582 587
disorder n/a 590 604
disorder n/a 630 642
disorder n/a 646 647
disorder n/a 669 674
coiled_coil n/a 711 736
disorder n/a 713 714
low_complexity n/a 714 737
disorder n/a 718 739

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O95202. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASILLRSCR GRAPARLPPP PRYTVPRGSP GDPAHLSCAS TLGLRNCLNV
50
51
PFGCCTPIHP VYTSSRGDHL GCWALRPECL RIVSRAPWTS TSVGFVAVGP
100
101
QCLPVRGWHS SRPVRDDSVV EKSLKSLKDK NKKLEEGGPV YSPPAEVVVK
150
151
KSLGQRVLDE LKHYYHGFRL LWIDTKIAAR MLWRILNGHS LTRRERRQFL
200
201
RICADLFRLV PFLVFVVVPF MEFLLPVAVK LFPNMLPSTF ETQSLKEERL
250
251
KKELRVKLEL AKFLQDTIEE MALKNKAAKG SATKDFSVFF QKIRETGERP
300
301
SNEEIMRFSK LFEDELTLDN LTRPQLVALC KLLELQSIGT NNFLRFQLTM
350
351
RLRSIKADDK LIAEEGVDSL NVKELQAACR ARGMRALGVT EDRLRGQLKQ
400
401
WLDLHLHQEI PTSLLILSRA MYLPDTLSPA DQLKSTLQTL PEIVAKEAQV
450
451
KVAEVEGEQV DNKAKLEATL QEEAAIQQEH REKELQKRSE VAKDFEPERV
500
501
VAAPQRPGTE PQPEMPDTVL QSETLKDTAP VLEGLKEEEI TKEEIDILSD
550
551
ACSKLQEQKK SLTKEKEELE LLKEDVQDYS EDLQEIKKEL SKTGEEKYVE
600
601
ESKASKRLTK RVQQMIGQID GLISQLEMDQ QAGKLAPANG MPTGENVISV
650
651
AELINAMKQV KHIPESKLTS LAAALDENKD GKVNIDDLVK VIELVDKEDV
700
701
HISTSQVAEI VATLEKEEKV EEKEKAKEKA EKEVAEVKS            
739
 

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Checksums:
CRC64:942E9138F299D94F
MD5:48d39148e88bfa065c3565a4033e3e76

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.