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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: KI20A_HUMAN (O95235)

Summary

This is the summary of UniProt entry KI20A_HUMAN (O95235).

Description: Kinesin-like protein KIF20A
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 890 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 51 56
Pfam Kinesin 70 507
low_complexity n/a 265 274
disorder n/a 278 285
disorder n/a 325 330
disorder n/a 370 372
low_complexity n/a 377 391
disorder n/a 420 422
disorder n/a 426 428
disorder n/a 454 456
disorder n/a 535 537
disorder n/a 540 546
disorder n/a 550 551
low_complexity n/a 573 585
disorder n/a 604 605
low_complexity n/a 615 626
coiled_coil n/a 634 668
low_complexity n/a 638 652
disorder n/a 648 649
low_complexity n/a 649 661
disorder n/a 659 660
disorder n/a 665 669
low_complexity n/a 670 690
disorder n/a 674 677
coiled_coil n/a 682 716
disorder n/a 709 722
disorder n/a 724 731
coiled_coil n/a 734 761
disorder n/a 825 854
low_complexity n/a 833 844
disorder n/a 884 886

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O95235. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSQGILSPPA GLLSDDDVVV SPMFESTAAD LGSVVRKNLL SDCSVVSTSL
50
51
EDKQQVPSED SMEKVKVYLR VRPLLPSELE RQEDQGCVRI ENVETLVLQA
100
101
PKDSFALKSN ERGIGQATHR FTFSQIFGPE VGQASFFNLT VKEMVKDVLK
150
151
GQNWLIYTYG VTNSGKTHTI QGTIKDGGIL PRSLALIFNS LQGQLHPTPD
200
201
LKPLLSNEVI WLDSKQIRQE EMKKLSLLNG GLQEEELSTS LKRSVYIESR
250
251
IGTSTSFDSG IAGLSSISQC TSSSQLDETS HRWAQPDTAP LPVPANIRFS
300
301
IWISFFEIYN ELLYDLLEPP SQQRKRQTLR LCEDQNGNPY VKDLNWIHVQ
350
351
DAEEAWKLLK VGRKNQSFAS THLNQNSSRS HSIFSIRILH LQGEGDIVPK
400
401
ISELSLCDLA GSERCKDQKS GERLKEAGNI NTSLHTLGRC IAALRQNQQN
450
451
RSKQNLVPFR DSKLTRVFQG FFTGRGRSCM IVNVNPCAST YDETLHVAKF
500
501
SAIASQLVHA PPMQLGFPSL HSFIKEHSLQ VSPSLEKGAK ADTGLDDDIE
550
551
NEADISMYGK EELLQVVEAM KTLLLKERQE KLQLEMHLRD EICNEMVEQM
600
601
QQREQWCSEH LDTQKELLEE MYEEKLNILK ESLTSFYQEE IQERDEKIEE
650
651
LEALLQEARQ QSVAHQQSGS ELALRRSQRL AASASTQQLQ EVKAKLQQCK
700
701
AELNSTTEEL HKYQKMLEPP PSAKPFTIDV DKKLEEGQKN IRLLRTELQK
750
751
LGESLQSAER ACCHSTGAGK LRQALTTCDD ILIKQDQTLA ELQNNMVLVK
800
801
LDLRKKAACI AEQYHTVLKL QGQVSAKKRL GTNQENQQPN QQPPGKKPFL
850
851
RNLLPRTPTC QSSTDCSPYA RILRSRRSPL LKSGPFGKKY           
890
 

Show the unformatted sequence.

Checksums:
CRC64:6620264615496051
MD5:7674760d15e1e3ebf129f200689e19ea

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;