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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ATS2_HUMAN (O95450)

Summary

This is the summary of UniProt entry ATS2_HUMAN (O95450).

Description: A disintegrin and metalloproteinase with thrombospondin motifs 2 EC=3.4.24.14
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 1211 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 42
low_complexity n/a 2 49
disorder n/a 31 48
disorder n/a 50 58
Pfam Pep_M12B_propep 57 212
low_complexity n/a 73 94
disorder n/a 87 101
disorder n/a 103 104
disorder n/a 133 144
low_complexity n/a 184 194
disorder n/a 208 227
low_complexity n/a 225 242
low_complexity n/a 253 264
disorder n/a 254 258
Pfam Reprolysin 267 470
Pfam ADAM_CR_2 482 551
Pfam TSP_1 565 615
Pfam ADAM_spacer1 723 837
Pfam TSP_1 858 913
Pfam TSP_1 919 975
disorder n/a 954 955
disorder n/a 957 958
Pfam TSP_1 980 1028
disorder n/a 1039 1045
disorder n/a 1055 1058
disorder n/a 1101 1120
disorder n/a 1127 1204
disorder n/a 1206 1207
disorder n/a 1209 1211

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O95450. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDPPAGAARR LLCPALLLLL LLLPPPLLPP PPPPANARLA AAADPPGGPL
50
51
GHGAERILAV PVRTDAQGRL VSHVVSAATS RAGVRARRAA PVRTPSFPGG
100
101
NEEEPGSHLF YNVTVFGRDL HLRLRPNARL VAPGATMEWQ GEKGTTRVEP
150
151
LLGSCLYVGD VAGLAEASSV ALSNCDGLAG LIRMEEEEFF IEPLEKGLAA
200
201
QEAEQGRVHV VYRRPPTSPP LGGPQALDTG ASLDSLDSLS RALGVLEEHA
250
251
NSSRRRARRH AADDDYNIEV LLGVDDSVVQ FHGKEHVQKY LLTLMNIVNE
300
301
IYHDESLGAH INVVLVRIIL LSYGKSMSLI EIGNPSQSLE NVCRWAYLQQ
350
351
KPDTGHDEYH DHAIFLTRQD FGPSGMQGYA PVTGMCHPVR SCTLNHEDGF
400
401
SSAFVVAHET GHVLGMEHDG QGNRCGDEVR LGSIMAPLVQ AAFHRFHWSR
450
451
CSQQELSRYL HSYDCLLDDP FAHDWPALPQ LPGLHYSMNE QCRFDFGLGY
500
501
MMCTAFRTFD PCKQLWCSHP DNPYFCKTKK GPPLDGTMCA PGKHCFKGHC
550
551
IWLTPDILKR DGSWGAWSPF GSCSRTCGTG VKFRTRQCDN PHPANGGRTC
600
601
SGLAYDFQLC SRQDCPDSLA DFREEQCRQW DLYFEHGDAQ HHWLPHEHRD
650
651
AKERCHLYCE SRETGEVVSM KRMVHDGTRC SYKDAFSLCV RGDCRKVGCD
700
701
GVIGSSKQED KCGVCGGDNS HCKVVKGTFT RSPKKHGYIK MFEIPAGARH
750
751
LLIQEVDATS HHLAVKNLET GKFILNEEND VDASSKTFIA MGVEWEYRDE
800
801
DGRETLQTMG PLHGTITVLV IPVGDTRVSL TYKYMIHEDS LNVDDNNVLE
850
851
EDSVVYEWAL KKWSPCSKPC GGGSQFTKYG CRRRLDHKMV HRGFCAALSK
900
901
PKAIRRACNP QECSQPVWVT GEWEPCSQTC GRTGMQVRSV RCIQPLHDNT
950
951
TRSVHAKHCN DARPESRRAC SRELCPGRWR AGPWSQCSVT CGNGTQERPV
1000
1001
LCRTADDSFG ICQEERPETA RTCRLGPCPR NISDPSKKSY VVQWLSRPDP
1050
1051
DSPIRKISSK GHCQGDKSIF CRMEVLSRYC SIPGYNKLCC KSCNLYNNLT
1100
1101
NVEGRIEPPP GKHNDIDVFM PTLPVPTVAM EVRPSPSTPL EVPLNASSTN
1150
1151
ATEDHPETNA VDEPYKIHGL EDEVQPPNLI PRRPSPYEKT RNQRIQELID
1200
1201
EMRKKEMLGK F                                          
1211
 

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Checksums:
CRC64:6C4F2C2D46A1F925
MD5:c69f338c01dd1a8d22ff885519512423

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.