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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: AGRL2_HUMAN (O95490)

Summary

This is the summary of UniProt entry AGRL2_HUMAN (O95490).

Description: Adhesion G protein-coupled receptor L2 {ECO:0000303|PubMed:25713288}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 1459 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 29
Pfam Gal_Lectin 49 129
Pfam OLF 140 392
low_complexity n/a 415 424
disorder n/a 425 456
Pfam HRM 466 524
disorder n/a 480 492
Pfam GAIN 538 760
disorder n/a 540 544
disorder n/a 583 593
disorder n/a 624 625
disorder n/a 627 629
disorder n/a 636 637
Pfam GPS 786 830
Pfam 7tm_2 844 1080
transmembrane n/a 845 870
transmembrane n/a 882 900
transmembrane n/a 906 930
low_complexity n/a 912 925
transmembrane n/a 951 971
transmembrane n/a 991 1014
low_complexity n/a 997 1012
transmembrane n/a 1035 1058
low_complexity n/a 1037 1048
transmembrane n/a 1064 1087
Pfam Latrophilin 1100 1459
low_complexity n/a 1118 1131
disorder n/a 1119 1124
disorder n/a 1139 1140
disorder n/a 1174 1175
disorder n/a 1183 1184
disorder n/a 1206 1224
disorder n/a 1275 1276
disorder n/a 1278 1281
disorder n/a 1283 1290
disorder n/a 1294 1296
disorder n/a 1298 1325
disorder n/a 1327 1332
disorder n/a 1334 1343
disorder n/a 1346 1410
disorder n/a 1418 1421
disorder n/a 1436 1459

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O95490. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVSSGCRMRS LWFIIVISFL PNTEGFSRAA LPFGLVRREL SCEGYSIDLR
50
51
CPGSDVIMIE SANYGRTDDK ICDADPFQME NTDCYLPDAF KIMTQRCNNR
100
101
TQCIVVTGSD VFPDPCPGTY KYLEVQYECV PYIFVCPGTL KAIVDSPCIY
150
151
EAEQKAGAWC KDPLQAADKI YFMPWTPYRT DTLIEYASLE DFQNSRQTTT
200
201
YKLPNRVDGT GFVVYDGAVF FNKERTRNIV KFDLRTRIKS GEAIINYANY
250
251
HDTSPYRWGG KTDIDLAVDE NGLWVIYATE QNNGMIVISQ LNPYTLRFEA
300
301
TWETVYDKRA ASNAFMICGV LYVVRSVYQD NESETGKNSI DYIYNTRLNR
350
351
GEYVDVPFPN QYQYIAAVDY NPRDNQLYVW NNNFILRYSL EFGPPDPAQV
400
401
PTTAVTITSS AELFKTIIST TSTTSQKGPM STTVAGSQEG SKGTKPPPAV
450
451
STTKIPPITN IFPLPERFCE ALDSKGIKWP QTQRGMMVER PCPKGTRGTA
500
501
SYLCMISTGT WNPKGPDLSN CTSHWVNQLA QKIRSGENAA SLANELAKHT
550
551
KGPVFAGDVS SSVRLMEQLV DILDAQLQEL KPSEKDSAGR SYNKLQKREK
600
601
TCRAYLKAIV DTVDNLLRPE ALESWKHMNS SEQAHTATML LDTLEEGAFV
650
651
LADNLLEPTR VSMPTENIVL EVAVLSTEGQ IQDFKFPLGI KGAGSSIQLS
700
701
ANTVKQNSRN GLAKLVFIIY RSLGQFLSTE NATIKLGADF IGRNSTIAVN
750
751
SHVISVSINK ESSRVYLTDP VLFTLPHIDP DNYFNANCSF WNYSERTMMG
800
801
YWSTQGCKLV DTNKTRTTCA CSHLTNFAIL MAHREIAYKD GVHELLLTVI
850
851
TWVGIVISLV CLAICIFTFC FFRGLQSDRN TIHKNLCINL FIAEFIFLIG
900
901
IDKTKYAIAC PIFAGLLHFF FLAAFAWMCL EGVQLYLMLV EVFESEYSRK
950
951
KYYYVAGYLF PATVVGVSAA IDYKSYGTEK ACWLHVDNYF IWSFIGPVTF
1000
1001
IILLNIIFLV ITLCKMVKHS NTLKPDSSRL ENIKSWVLGA FALLCLLGLT
1050
1051
WSFGLLFINE ETIVMAYLFT IFNAFQGVFI FIFHCALQKK VRKEYGKCFR
1100
1101
HSYCCGGLPT ESPHSSVKAS TTRTSARYSS GTQSRIRRMW NDTVRKQSES
1150
1151
SFISGDINST STLNQGMTGN YLLTNPLLRP HGTNNPYNTL LAETVVCNAP
1200
1201
SAPVFNSPGH SLNNARDTSA MDTLPLNGNF NNSYSLHKGD YNDSVQVVDC
1250
1251
GLSLNDTAFE KMIISELVHN NLRGSSKTHN LELTLPVKPV IGGSSSEDDA
1300
1301
IVADASSLMH SDNPGLELHH KELEAPLIPQ RTHSLLYQPQ KKVKSEGTDS
1350
1351
YVSQLTAEAE DHLQSPNRDS LYTSMPNLRD SPYPESSPDM EEDLSPSRRS
1400
1401
ENEDIYYKSM PNLGAGHQLQ MCYQISRGNS DGYIIPINKE GCIPEGDVRE
1450
1451
GQMQLVTSL                                             
1459
 

Show the unformatted sequence.

Checksums:
CRC64:30707B7C3C069029
MD5:6fb57a1184b76ac03fa4611291580edb

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.