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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CLD1_HUMAN (O95832)

Summary

This is the summary of UniProt entry CLD1_HUMAN (O95832).

Description: Claudin-1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 211 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 21
Pfam PMP22_Claudin 4 182
transmembrane n/a 79 98
low_complexity n/a 118 135
transmembrane n/a 119 141
transmembrane n/a 161 184
low_complexity n/a 169 185
low_complexity n/a 186 205
disorder n/a 195 199

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O95832. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MANAGLQLLG FILAFLGWIG AIVSTALPQW RIYSYAGDNI VTAQAMYEGL
50
51
WMSCVSQSTG QIQCKVFDSL LNLSSTLQAT RALMVVGILL GVIAIFVATV
100
101
GMKCMKCLED DEVQKMRMAV IGGAIFLLAG LAILVATAWY GNRIVQEFYD
150
151
PMTPVNARYE FGQALFTGWA AASLCLLGGA LLCCSCPRKT TSYPTPRPYP
200
201
KPAPSSGKDY V                                          
211
 

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Checksums:
CRC64:07269000E6C214F0
MD5:fc088de5faf46e844eaf974705a6993f

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.