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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GPAN1_HUMAN (O95872)

Summary

This is the summary of UniProt entry GPAN1_HUMAN (O95872).

Description: G patch domain and ankyrin repeat-containing protein 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 356 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 42
disorder n/a 44 112
low_complexity n/a 65 81
low_complexity n/a 78 88
Pfam Ank_4 104 163
disorder n/a 114 131
low_complexity n/a 117 126
disorder n/a 186 223
disorder n/a 228 254
Pfam G-patch 255 299
disorder n/a 266 269
disorder n/a 271 305
disorder n/a 307 320
disorder n/a 323 334
low_complexity n/a 332 339

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O95872. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSRPLLITFT PATDPSDLWK DGQQQPQPEK PESTLDGAAA RAFYEALIGD
50
51
ESSAPDSQRS QTEPARERKR KKRRIMKAPA AEAVAEGASG RHGQGRSLEA
100
101
EDKMTHRILR AAQEGDLPEL RRLLEPHEAG GAGGNINARD AFWWTPLMCA
150
151
ARAGQGAAVS YLLGRGAAWV GVCELSGRDA AQLAEEAGFP EVARMVRESH
200
201
GETRSPENRS PTPSLQYCEN CDTHFQDSNH RTSTAHLLSL SQGPQPPNLP
250
251
LGVPISSPGF KLLLRGGWEP GMGLGPRGEG RANPIPTVLK RDQEGLGYRS
300
301
APQPRVTHFP AWDTRAVAGR ERPPRVATLS WREERRREEK DRAWERDLRT
350
351
YMNLEF                                                
356
 

Show the unformatted sequence.

Checksums:
CRC64:AA57AA938A8C10E5
MD5:b0a190d7f490abc19ae961d96ce57026

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;