Summary
This is the summary of UniProt entry FRITZ_HUMAN (O95876).
| Description: | WD repeat-containing and planar cell polarity effector protein fritz homolog |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
| Length: | 746 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
Show or hide the data used to generate the graphic in JSON format.
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 70 | 71 |
| disorder | n/a | 73 | 78 |
| Pfam | Frtz | 79 | 622 |
| coiled_coil | n/a | 104 | 124 |
| low_complexity | n/a | 129 | 143 |
| disorder | n/a | 666 | 674 |
| disorder | n/a | 682 | 683 |
| disorder | n/a | 718 | 732 |
Show or hide domain scores.
Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O95876. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MRREFCWDAY SKAAGSRASS PLPRQDRDSF CHQMSFCLTE LHLWSLKNTL
50 51
HIADRDIGIY QYYDKKDPPA TEHGNLEKKQ KLAESRDYPW TLKNRRPEKL
100 101
RDSLKELEEL MQNSRCVLSK WKNKYVCQLL FGSGVLVSLS LSGPQLEKVV
150 151
IDRSLVGKLI SDTISDALLT DSFIILSFLA QNKLCFIQFT KKMESSDVNK
200 201
RLEKLSALDY KIFYYEIPGP INKTTERHLA INCVHDRVVC WWPLVNDDAW
250 251
PWAPISSEKD RANLLLLGYA QGRLEVLSSV RTEWDPLDVR FGTKQPYQVF
300 301
TVEHSVSVDK EPMADSCIYE CIRNKIQCVS VTRIPLKSKA ISCCRNVTED
350 351
KLILGCEDSS LILYETHRRV TLLAQTELLP SLISCHPSGA ILLVGSNQGE
400 401
LQIFDMALSP INIQLLAEDR LPRETLQFSK LFDASSSLVQ MQWIAPQVVS
450 451
QKGEGSDIYD LLFLRFERGP LGVLLFKLGV FTRGQLGLID IIFQYIHCDE
500 501
IYEAINILSS MNWDTLGHQC FISMSAIVNH LLRQKLTPER EAQLETSLGT
550 551
FYAPTRPLLD STILEYRDQI SKYARRFFHH LLRYQRFEKA FLLAVDVGAR
600 601
DLFMDIHYLA LDKGELALAE VARKRASDID AESITSGVEL LGPLDRGDML
650 651
NEAFIGLSLA PQGEDSFPDN LPPSCPTHRH ILQQRILNGS SNRQIIDRRN
700 701
ELEKDICSGF LMTNTCNAED GELREDGREQ EIRDGGSLKM IHFGLV
746
Show the unformatted sequence. |
| Checksums: |
CRC64:585EFED0D93EB3D4
MD5:3a2f83ff991b3e66d14d627fa81b470c
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
| Very High (pLDDT > 90) | |
| Confident (90 > pLDDT > 70) | |
| Low (70 > pLDDT > 50) | |
| Very Low (pLDDT < 50) |
