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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: CYB5_HUMAN (P00167)

Summary

This is the summary of UniProt entry CYB5_HUMAN (P00167).

Description: Cytochrome b5
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 134 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 11 14
Pfam Cyt-b5 13 85
disorder n/a 46 68
disorder n/a 79 80
disorder n/a 86 87
disorder n/a 90 97
low_complexity n/a 97 110
transmembrane n/a 109 130

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P00167. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAEQSDEAVK YYTLEEIQKH NHSKSTWLIL HHKVYDLTKF LEEHPGGEEV
50
51
LREQAGGDAT ENFEDVGHST DAREMSKTFI IGELHPDDRP KLNKPPETLI
100
101
TTIDSSSSWW TNWVIPAISA VAVALMYRLY MAED                 
134
 

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Checksums:
CRC64:B6AD2AB747555048
MD5:3542ab8f52b4b6e5c94655baf3033133

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Cyt-b5 13 - 85 2I96 A 33 - 105 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.