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11  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: AL1A1_HUMAN (P00352)

Summary

This is the summary of UniProt entry AL1A1_HUMAN (P00352).

Description: Retinal dehydrogenase 1 {ECO:0000305}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 501 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Aldedh 29 492
disorder n/a 51 53
disorder n/a 342 343

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P00352. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSSSGTPDLP VLLTDLKIQY TKIFINNEWH DSVSGKKFPV FNPATEEELC
50
51
QVEEGDKEDV DKAVKAARQA FQIGSPWRTM DASERGRLLY KLADLIERDR
100
101
LLLATMESMN GGKLYSNAYL NDLAGCIKTL RYCAGWADKI QGRTIPIDGN
150
151
FFTYTRHEPI GVCGQIIPWN FPLVMLIWKI GPALSCGNTV VVKPAEQTPL
200
201
TALHVASLIK EAGFPPGVVN IVPGYGPTAG AAISSHMDID KVAFTGSTEV
250
251
GKLIKEAAGK SNLKRVTLEL GGKSPCIVLA DADLDNAVEF AHHGVFYHQG
300
301
QCCIAASRIF VEESIYDEFV RRSVERAKKY ILGNPLTPGV TQGPQIDKEQ
350
351
YDKILDLIES GKKEGAKLEC GGGPWGNKGY FVQPTVFSNV TDEMRIAKEE
400
401
IFGPVQQIMK FKSLDDVIKR ANNTFYGLSA GVFTKDIDKA ITISSALQAG
450
451
TVWVNCYGVV SAQCPFGGFK MSGNGRELGE YGFHEYTEVK TVTVKISQKN
500
501
S                                                     
501
 

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Checksums:
CRC64:B26464DC7168348E
MD5:90dcf2406e7554f880306838be2c070a

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Aldedh 29 - 492 4WB9 A 29 - 492 Jmol OpenAstexViewer
4WJ9 A 29 - 492 Jmol OpenAstexViewer
4WP7 A 29 - 492 Jmol OpenAstexViewer
4WPN A 29 - 492 Jmol OpenAstexViewer
4X4L A 29 - 492 Jmol OpenAstexViewer
5AC2 A 29 - 492 Jmol OpenAstexViewer
5L2M A 29 - 492 Jmol OpenAstexViewer
5L2N A 29 - 492 Jmol OpenAstexViewer
5L2O A 29 - 492 Jmol OpenAstexViewer
B 29 - 492 Jmol OpenAstexViewer
C 29 - 492 Jmol OpenAstexViewer
D 29 - 492 Jmol OpenAstexViewer
E 29 - 492 Jmol OpenAstexViewer
F 29 - 492 Jmol OpenAstexViewer
G 29 - 492 Jmol OpenAstexViewer
H 29 - 492 Jmol OpenAstexViewer
5TEI A 29 - 492 Jmol OpenAstexViewer
6DUM A 29 - 492 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.