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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: COX3_HUMAN (P00414)

Summary

This is the summary of UniProt entry COX3_HUMAN (P00414).

Description: Cytochrome c oxidase subunit 3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 261 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam COX3 6 261
transmembrane n/a 16 35
low_complexity n/a 39 53
transmembrane n/a 41 58
transmembrane n/a 79 102
low_complexity n/a 91 100
transmembrane n/a 129 147
transmembrane n/a 159 177
transmembrane n/a 197 220
transmembrane n/a 240 260

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P00414. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTHQSHAYHM VKPSPWPLTG ALSALLMTSG LAMWFHFHSM TLLMLGLLTN
50
51
TLTMYQWWRD VTRESTYQGH HTPPVQKGLR YGMILFITSE VFFFAGFFWA
100
101
FYHSSLAPTP QLGGHWPPTG ITPLNPLEVP LLNTSVLLAS GVSITWAHHS
150
151
LMENNRNQMI QALLITILLG LYFTLLQASE YFESPFTISD GIYGSTFFVA
200
201
TGFHGLHVII GSTFLTICFI RQLMFHFTSK HHFGFEAAAW YWHFVDVVWL
250
251
FLYVSIYWWG S                                          
261
 

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Checksums:
CRC64:A04385EF748B7C14
MD5:324fcf272310c7b7ae0dc7aa4de7c5c5

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
COX3 6 - 261 5Z62 C 6 - 261 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.