Summary
This is the summary of UniProt entry CHYM_BOVIN (P00794).
| Description: | Chymosin EC=3.4.23.4 |
| Source organism: |
Bos taurus (Bovine)
(NCBI taxonomy ID
9913)
|
| Length: | 381 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
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| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 16 |
| Pfam | A1_Propeptide | 19 | 47 |
| Pfam | Asp | 73 | 380 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P00794. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MRCLVVLLAV FALSQGAEIT RIPLYKGKSL RKALKEHGLL EDFLQKQQYG
50 51
ISSKYSGFGE VASVPLTNYL DSQYFGKIYL GTPPQEFTVL FDTGSSDFWV
100 101
PSIYCKSNAC KNHQRFDPRK SSTFQNLGKP LSIHYGTGSM QGILGYDTVT
150 151
VSNIVDIQQT VGLSTQEPGD VFTYAEFDGI LGMAYPSLAS EYSIPVFDNM
200 201
MNRHLVAQDL FSVYMDRNGQ ESMLTLGAID PSYYTGSLHW VPVTVQQYWQ
250 251
FTVDSVTISG VVVACEGGCQ AILDTGTSKL VGPSSDILNI QQAIGATQNQ
300 301
YGEFDIDCDN LSYMPTVVFE INGKMYPLTP SAYTSQDQGF CTSGFQSENH
350 351
SQKWILGDVF IREYYSVFDR ANNLVGLAKA I
381
Show the unformatted sequence. |
| Checksums: |
CRC64:A4425013B4E2E56A
MD5:902a69ef9a51ea1d5d05927cdfda09ae
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| Asp | 73 - 380 | 1CMS | A | 15 - 322 | Jmol OpenAstexViewer |
| 1CZI | E | 13 - 325 | Jmol OpenAstexViewer | ||
| 3CMS | A | 13 - 325 | Jmol OpenAstexViewer | ||
| 4AA8 | A | 15 - 322 | Jmol OpenAstexViewer | ||
| 4AUC | A | 15 - 322 | Jmol OpenAstexViewer | ||
| 4CMS | A | 13 - 325 | Jmol OpenAstexViewer |
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
