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8  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SYA_ECOLI (P00957)

Summary

This is the summary of UniProt entry SYA_ECOLI (P00957).

Description: Alanine--tRNA ligase EC=6.1.1.7
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 876 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam tRNA-synt_2c 7 556
disorder n/a 65 66
low_complexity n/a 194 205
disorder n/a 196 200
disorder n/a 227 232
coiled_coil n/a 346 366
disorder n/a 353 355
low_complexity n/a 425 438
disorder n/a 429 430
Pfam tRNA_SAD 653 696
coiled_coil n/a 725 759
Pfam DHHA1 732 871
low_complexity n/a 740 756
disorder n/a 747 749
disorder n/a 843 852
low_complexity n/a 849 864

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P00957. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSKSTAEIRQ AFLDFFHSKG HQVVASSSLV PHNDPTLLFT NAGMNQFKDV
50
51
FLGLDKRNYS RATTSQRCVR AGGKHNDLEN VGYTARHHTF FEMLGNFSFG
100
101
DYFKHDAIQF AWELLTSEKW FALPKERLWV TVYESDDEAY EIWEKEVGIP
150
151
RERIIRIGDN KGAPYASDNF WQMGDTGPCG PCTEIFYDHG DHIWGGPPGS
200
201
PEEDGDRYIE IWNIVFMQFN RQADGTMEPL PKPSVDTGMG LERIAAVLQH
250
251
VNSNYDIDLF RTLIQAVAKV TGATDLSNKS LRVIADHIRS CAFLIADGVM
300
301
PSNENRGYVL RRIIRRAVRH GNMLGAKETF FYKLVGPLID VMGSAGEDLK
350
351
RQQAQVEQVL KTEEEQFART LERGLALLDE ELAKLSGDTL DGETAFRLYD
400
401
TYGFPVDLTA DVCRERNIKV DEAGFEAAME EQRRRAREAS GFGADYNAMI
450
451
RVDSASEFKG YDHLELNGKV TALFVDGKAV DAINAGQEAV VVLDQTPFYA
500
501
ESGGQVGDKG ELKGANFSFA VEDTQKYGQA IGHIGKLAAG SLKVGDAVQA
550
551
DVDEARRARI RLNHSATHLM HAALRQVLGT HVSQKGSLVN DKVLRFDFSH
600
601
NEAMKPEEIR AVEDLVNTQI RRNLPIETNI MDLEAAKAKG AMALFGEKYD
650
651
ERVRVLSMGD FSTELCGGTH ASRTGDIGLF RIISESGTAA GVRRIEAVTG
700
701
EGAIATVHAD SDRLSEVAHL LKGDSNNLAD KVRSVLERTR QLEKELQQLK
750
751
EQAAAQESAN LSSKAIDVNG VKLLVSELSG VEPKMLRTMV DDLKNQLGST
800
801
IIVLATVVEG KVSLIAGVSK DVTDRVKAGE LIGMVAQQVG GKGGGRPDMA
850
851
QAGGTDAAAL PAALASVKGW VSAKLQ                          
876
 

Show the unformatted sequence.

Checksums:
CRC64:73F69C69FCF8C08C
MD5:7e88afdd0d0a0c72076b8ed02b3c7385

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
tRNA-synt_2c 7 - 438 3HY1 B 6 - 437 Jmol OpenAstexViewer
7 - 441 3HY1 A 6 - 440 Jmol OpenAstexViewer
7 - 442 3HXU A 6 - 441 Jmol OpenAstexViewer
3HXV A 6 - 441 Jmol OpenAstexViewer
3HXW A 6 - 441 Jmol OpenAstexViewer
3HXX A 6 - 441 Jmol OpenAstexViewer
3HXY A 6 - 441 Jmol OpenAstexViewer
3HXZ A 6 - 441 Jmol OpenAstexViewer
B 6 - 441 Jmol OpenAstexViewer
C 6 - 441 Jmol OpenAstexViewer
D 6 - 441 Jmol OpenAstexViewer
3HY0 A 6 - 441 Jmol OpenAstexViewer
B 6 - 441 Jmol OpenAstexViewer