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9  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CYTC_HUMAN (P01034)

Summary

This is the summary of UniProt entry CYTC_HUMAN (P01034).

Description: Cystatin-C
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 146 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 26
low_complexity n/a 1 32
disorder n/a 28 41
Pfam Cystatin 37 132
disorder n/a 103 110

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P01034. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAGPLRAPLL LLAILAVALA VSPAAGSSPG KPPRLVGGPM DASVEEEGVR
50
51
RALDFAVGEY NKASNDMYHS RALQVVRARK QIVAGVNYFL DVELGRTTCT
100
101
KTQPNLDNCP FHDQPHLKRK AFCSFQIYAV PWQGTMTLSK STCQDA    
146
 

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Checksums:
CRC64:75EF049CAE2E8B2B
MD5:5c6e46e212bc7342fa9e74d7ec3b2a0c

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Cystatin 37 - 132 1G96 A 11 - 106 Jmol OpenAstexViewer
1R4C A 11 - 106 Jmol OpenAstexViewer
B 11 - 106 Jmol OpenAstexViewer
C 11 - 106 Jmol OpenAstexViewer
D 11 - 106 Jmol OpenAstexViewer
E 11 - 106 Jmol OpenAstexViewer
F 11 - 106 Jmol OpenAstexViewer
G 11 - 106 Jmol OpenAstexViewer
H 11 - 106 Jmol OpenAstexViewer
1TIJ A 11 - 106 Jmol OpenAstexViewer
B 11 - 106 Jmol OpenAstexViewer
3QRD A 11 - 106 Jmol OpenAstexViewer
D 11 - 106 Jmol OpenAstexViewer
3S67 A 11 - 106 Jmol OpenAstexViewer
3SVA A 11 - 106 Jmol OpenAstexViewer
38 - 132 3GAX A 12 - 106 Jmol OpenAstexViewer
B 12 - 106 Jmol OpenAstexViewer
3NX0 A 12 - 106 Jmol OpenAstexViewer
B 12 - 106 Jmol OpenAstexViewer
3PS8 A 12 - 106 Jmol OpenAstexViewer
3QRD B 12 - 106 Jmol OpenAstexViewer
39 - 132 3QRD C 13 - 106 Jmol OpenAstexViewer