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82  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RASK_HUMAN (P01116)

Summary

This is the summary of UniProt entry RASK_HUMAN (P01116).

Description: GTPase KRas
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 189 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Ras 5 165
low_complexity n/a 6 14

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P01116. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET
50
51
CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI
100
101
KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ
150
151
RVEDAFYTLV REIRQYRLKK ISKEEKTPGC VKIKKCIIM            
189
 

Show the unformatted sequence.

Checksums:
CRC64:973547B2E11C2C81
MD5:4a8c310887927cecc35b9de4b784596e

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ras 5 - 164 5MLA A 5 - 164 Jmol OpenAstexViewer
5MLB G 5 - 164 Jmol OpenAstexViewer
5O2S G 5 - 164 Jmol OpenAstexViewer
5O2T A 5 - 164 Jmol OpenAstexViewer
5WPM A 5 - 164 Jmol OpenAstexViewer
5 - 165 3GFT A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
D 5 - 165 Jmol OpenAstexViewer
E 5 - 165 Jmol OpenAstexViewer
F 5 - 165 Jmol OpenAstexViewer
4DSN A 5 - 165 Jmol OpenAstexViewer
4DSO A 5 - 165 Jmol OpenAstexViewer
4DST A 5 - 165 Jmol OpenAstexViewer
4DSU A 5 - 165 Jmol OpenAstexViewer
4EPR A 5 - 165 Jmol OpenAstexViewer
4EPT A 5 - 165 Jmol OpenAstexViewer
4EPV A 5 - 165 Jmol OpenAstexViewer
4EPW A 5 - 165 Jmol OpenAstexViewer
4EPX A 5 - 165 Jmol OpenAstexViewer
4EPY A 5 - 165 Jmol OpenAstexViewer
4L8G A 5 - 165 Jmol OpenAstexViewer
4LDJ A 5 - 165 Jmol OpenAstexViewer
4LPK A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
4LRW A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
4LUC A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
4LV6 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
4LYF A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
4LYH A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
4LYJ A 5 - 165 Jmol OpenAstexViewer
4M1O A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
4M1S A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
4M1T A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
4M1W A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
4M1Y A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
4M21 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
4M22 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
4NMM A 5 - 165 Jmol OpenAstexViewer
4OBE A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
4PZY A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
4PZZ A 5 - 165 Jmol OpenAstexViewer
4Q01 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
4Q02 A 5 - 165 Jmol OpenAstexViewer
4Q03 A 5 - 165 Jmol OpenAstexViewer
4QL3 A 5 - 165 Jmol OpenAstexViewer
4TQ9 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
4TQA A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
4WA7 A 5 - 165 Jmol OpenAstexViewer
5F2E A 5 - 165 Jmol OpenAstexViewer
5KYK A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
5MLB A 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
E 5 - 165 Jmol OpenAstexViewer
5O2S A 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
E 5 - 165 Jmol OpenAstexViewer
5TAR A 5 - 165 Jmol OpenAstexViewer
5TB5 A 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
5UFE A 5 - 165 Jmol OpenAstexViewer
5UFQ A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5UK9 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5UQW A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5US4 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5USJ A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
D 5 - 165 Jmol OpenAstexViewer
E 5 - 165 Jmol OpenAstexViewer
F 5 - 165 Jmol OpenAstexViewer
5V6S A 5 - 165 Jmol OpenAstexViewer
5V6V A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5V71 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
D 5 - 165 Jmol OpenAstexViewer
E 5 - 165 Jmol OpenAstexViewer
F 5 - 165 Jmol OpenAstexViewer
5V9L A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
5V9O A 5 - 165 Jmol OpenAstexViewer
5V9U A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5VBM A 5 - 165 Jmol OpenAstexViewer
5VP7 A 5 - 165 Jmol OpenAstexViewer
F 5 - 165 Jmol OpenAstexViewer
5VPI A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5VPY A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5VPZ A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5VQ0 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5VQ1 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5VQ2 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5VQ6 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5VQ8 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5W22 A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
5WHA A 5 - 165 Jmol OpenAstexViewer
D 5 - 165 Jmol OpenAstexViewer
G 5 - 165 Jmol OpenAstexViewer
J 5 - 165 Jmol OpenAstexViewer
5WHB A 5 - 165 Jmol OpenAstexViewer
D 5 - 165 Jmol OpenAstexViewer
G 5 - 165 Jmol OpenAstexViewer
J 5 - 165 Jmol OpenAstexViewer
5WHD A 5 - 165 Jmol OpenAstexViewer
B 5 - 165 Jmol OpenAstexViewer
C 5 - 165 Jmol OpenAstexViewer
D 5 - 165 Jmol OpenAstexViewer
5WHE A 5 - 165 Jmol OpenAstexViewer
D 5 - 165 Jmol OpenAstexViewer
G 5 - 165 Jmol OpenAstexViewer
J 5 - 165 Jmol OpenAstexViewer
5WLB A 5 - 165 Jmol OpenAstexViewer
D 5 - 165 Jmol OpenAstexViewer
5XCO A 5 - 165 Jmol OpenAstexViewer
5YXZ A 5 - 165 Jmol OpenAstexViewer
5YY1 A 5 - 165 Jmol OpenAstexViewer
6ARK A 5 - 165 Jmol OpenAstexViewer
6ASA A 5 - 165 Jmol OpenAstexViewer
6ASE A 5 - 165 Jmol OpenAstexViewer
6BP1 A 5 - 165 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.