Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PIGR_HUMAN (P01833)

Summary

This is the summary of UniProt entry PIGR_HUMAN (P01833).

Description: Polymeric immunoglobulin receptor
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 764 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
sig_p n/a 1 17
Pfam V-set 23 128
Pfam V-set 136 238
disorder n/a 231 234
Pfam V-set 241 341
Pfam V-set 354 457
low_complexity n/a 357 368
Pfam V-set 465 562
disorder n/a 573 574
disorder n/a 610 612
disorder n/a 615 637
low_complexity n/a 626 636
transmembrane n/a 639 661
low_complexity n/a 643 660
disorder n/a 685 738
low_complexity n/a 712 731
low_complexity n/a 725 739
disorder n/a 752 764

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P01833. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLLFVLTCLL AVFPAISTKS PIFGPEEVNS VEGNSVSITC YYPPTSVNRH
50
51
TRKYWCRQGA RGGCITLISS EGYVSSKYAG RANLTNFPEN GTFVVNIAQL
100
101
SQDDSGRYKC GLGINSRGLS FDVSLEVSQG PGLLNDTKVY TVDLGRTVTI
150
151
NCPFKTENAQ KRKSLYKQIG LYPVLVIDSS GYVNPNYTGR IRLDIQGTGQ
200
201
LLFSVVINQL RLSDAGQYLC QAGDDSNSNK KNADLQVLKP EPELVYEDLR
250
251
GSVTFHCALG PEVANVAKFL CRQSSGENCD VVVNTLGKRA PAFEGRILLN
300
301
PQDKDGSFSV VITGLRKEDA GRYLCGAHSD GQLQEGSPIQ AWQLFVNEES
350
351
TIPRSPTVVK GVAGGSVAVL CPYNRKESKS IKYWCLWEGA QNGRCPLLVD
400
401
SEGWVKAQYE GRLSLLEEPG NGTFTVILNQ LTSRDAGFYW CLTNGDTLWR
450
451
TTVEIKIIEG EPNLKVPGNV TAVLGETLKV PCHFPCKFSS YEKYWCKWNN
500
501
TGCQALPSQD EGPSKAFVNC DENSRLVSLT LNLVTRADEG WYWCGVKQGH
550
551
FYGETAAVYV AVEERKAAGS RDVSLAKADA APDEKVLDSG FREIENKAIQ
600
601
DPRLFAEEKA VADTRDQADG SRASVDSGSS EEQGGSSRAL VSTLVPLGLV
650
651
LAVGAVAVGV ARARHRKNVD RVSIRSYRTD ISMSDFENSR EFGANDNMGA
700
701
SSITQETSLG GKEEFVATTE STTETKEPKK AKRSSKEEAE MAYKDFLLQS
750
751
STVAAEAQDG PQEA                                       
764
 

Show the unformatted sequence.

Checksums:
CRC64:927461F4EB3B05C7
MD5:db3a9e7cb77f5f87d3623833d03581fa

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
V-set 136 - 238 2OCW A 118 - 220 Jmol OpenAstexViewer
3CHN S 118 - 220 Jmol OpenAstexViewer
3CM9 S 118 - 220 Jmol OpenAstexViewer
5D4K A 118 - 220 Jmol OpenAstexViewer
B 118 - 220 Jmol OpenAstexViewer
23 - 127 1XED A 5 - 109 Jmol OpenAstexViewer
B 5 - 109 Jmol OpenAstexViewer
C 5 - 109 Jmol OpenAstexViewer
D 5 - 109 Jmol OpenAstexViewer
E 5 - 109 Jmol OpenAstexViewer
F 5 - 109 Jmol OpenAstexViewer
23 - 128 2OCW A 5 - 110 Jmol OpenAstexViewer
3CHN S 5 - 110 Jmol OpenAstexViewer
3CM9 S 5 - 110 Jmol OpenAstexViewer
5D4K A 5 - 110 Jmol OpenAstexViewer
B 5 - 110 Jmol OpenAstexViewer
241 - 341 2OCW A 223 - 323 Jmol OpenAstexViewer
3CHN S 223 - 323 Jmol OpenAstexViewer
3CM9 S 223 - 323 Jmol OpenAstexViewer
5D4K A 223 - 323 Jmol OpenAstexViewer
B 223 - 323 Jmol OpenAstexViewer
354 - 457 2OCW A 336 - 439 Jmol OpenAstexViewer
3CHN J 336 - 439 Jmol OpenAstexViewer
S 336 - 439 Jmol OpenAstexViewer
3CM9 J 336 - 439 Jmol OpenAstexViewer
S 336 - 439 Jmol OpenAstexViewer
5D4K A 336 - 439 Jmol OpenAstexViewer
B 336 - 439 Jmol OpenAstexViewer
465 - 562 2OCW A 447 - 544 Jmol OpenAstexViewer
3CHN S 447 - 544 Jmol OpenAstexViewer
3CM9 S 447 - 544 Jmol OpenAstexViewer
5D4K A 447 - 544 Jmol OpenAstexViewer
B 447 - 544 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.