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12  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DQA1_HUMAN (P01909)

Summary

This is the summary of UniProt entry DQA1_HUMAN (P01909).

Description: HLA class II histocompatibility antigen, DQ alpha 1 chain
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 254 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 23
Pfam MHC_II_alpha 29 108
Pfam C1-set 114 195
transmembrane n/a 221 239
low_complexity n/a 221 240

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P01909. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MILNKALMLG ALALTTVMSP CGGEDIVADH VASYGVNLYQ SYGPSGQYTH
50
51
EFDGDEQFYV DLGRKETVWC LPVLRQFRFD PQFALTNIAV LKHNLNSLIK
100
101
RSNSTAATNE VPEVTVFSKS PVTLGQPNIL ICLVDNIFPP VVNITWLSNG
150
151
HSVTEGVSET SFLSKSDHSF FKISYLTLLP SAEESYDCKV EHWGLDKPLL
200
201
KHWEPEIPAP MSELTETVVC ALGLSVGLVG IVVGTVFIIR GLRSVGASRH
250
251
QGPL                                                  
254
 

Show the unformatted sequence.

Checksums:
CRC64:84E12B5A80E2A028
MD5:3020800c0f1a3e5f3da33f3eaa1f17fe

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
C1-set 114 - 195 1JK8 A 89 - 170 Jmol OpenAstexViewer
1S9V A 89 - 170 Jmol OpenAstexViewer
D 89 - 170 Jmol OpenAstexViewer
2NNA A 89 - 170 Jmol OpenAstexViewer
4GG6 A 89 - 170 Jmol OpenAstexViewer
C 89 - 170 Jmol OpenAstexViewer
4OZF A 89 - 170 Jmol OpenAstexViewer
4OZG A 89 - 170 Jmol OpenAstexViewer
C 89 - 170 Jmol OpenAstexViewer
4OZH A 89 - 170 Jmol OpenAstexViewer
C 89 - 170 Jmol OpenAstexViewer
4OZI A 89 - 170 Jmol OpenAstexViewer
C 89 - 170 Jmol OpenAstexViewer
5KSA A 89 - 170 Jmol OpenAstexViewer
5KSB A 89 - 170 Jmol OpenAstexViewer
C 89 - 170 Jmol OpenAstexViewer
5KSU A 89 - 170 Jmol OpenAstexViewer
D 89 - 170 Jmol OpenAstexViewer
5KSV A 89 - 170 Jmol OpenAstexViewer
MHC_II_alpha 29 - 108 1JK8 A 4 - 83 Jmol OpenAstexViewer
1S9V A 4 - 83 Jmol OpenAstexViewer
D 4 - 83 Jmol OpenAstexViewer
2NNA A 4 - 83 Jmol OpenAstexViewer
4GG6 A 4 - 83 Jmol OpenAstexViewer
C 4 - 83 Jmol OpenAstexViewer
4OZF A 4 - 83 Jmol OpenAstexViewer
4OZG A 4 - 83 Jmol OpenAstexViewer
C 4 - 83 Jmol OpenAstexViewer
4OZH A 4 - 83 Jmol OpenAstexViewer
C 4 - 83 Jmol OpenAstexViewer
4OZI A 4 - 83 Jmol OpenAstexViewer
C 4 - 83 Jmol OpenAstexViewer
5KSA A 4 - 83 Jmol OpenAstexViewer
5KSB A 4 - 83 Jmol OpenAstexViewer
C 4 - 83 Jmol OpenAstexViewer
5KSU A 4 - 83 Jmol OpenAstexViewer
D 4 - 83 Jmol OpenAstexViewer
5KSV A 4 - 83 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.