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6  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CRP_HUMAN (P02741)

Summary

This is the summary of UniProt entry CRP_HUMAN (P02741).

Description: C-reactive protein
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 224 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 16
Pfam Pentaxin 25 220

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P02741. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEKLLCFLVL TSLSHAFGQT DMSRKAFVFP KESDTSYVSL KAPLTKPLKA
50
51
FTVCLHFYTE LSSTRGYSIF SYATKRQDNE ILIFWSKDIG YSFTVGGSEI
100
101
LFEVPEVTVA PVHICTSWES ASGIVEFWVD GKPRVRKSLK KGYTVGAEAS
150
151
IILGQEQDSF GGNFEGSQSL VGDIGNVNMW DFVLSPDEIN TIYLGGPFSP
200
201
NVLNWRALKY EVQGEVFTKP QLWP                            
224
 

Show the unformatted sequence.

Checksums:
CRC64:669228636A8544F6
MD5:6d970efc7133d164e2c145b62663adf8

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Pentaxin 25 - 220 1B09 A 7 - 202 Jmol OpenAstexViewer
B 7 - 202 Jmol OpenAstexViewer
C 7 - 202 Jmol OpenAstexViewer
D 7 - 202 Jmol OpenAstexViewer
E 7 - 202 Jmol OpenAstexViewer
1GNH A 7 - 202 Jmol OpenAstexViewer
B 7 - 202 Jmol OpenAstexViewer
C 7 - 202 Jmol OpenAstexViewer
D 7 - 202 Jmol OpenAstexViewer
E 7 - 202 Jmol OpenAstexViewer
F 7 - 202 Jmol OpenAstexViewer
G 7 - 202 Jmol OpenAstexViewer
H 7 - 202 Jmol OpenAstexViewer
I 7 - 202 Jmol OpenAstexViewer
J 7 - 202 Jmol OpenAstexViewer
1LJ7 A 7 - 202 Jmol OpenAstexViewer
B 7 - 202 Jmol OpenAstexViewer
C 7 - 202 Jmol OpenAstexViewer
D 7 - 202 Jmol OpenAstexViewer
E 7 - 202 Jmol OpenAstexViewer
F 7 - 202 Jmol OpenAstexViewer
G 7 - 202 Jmol OpenAstexViewer
H 7 - 202 Jmol OpenAstexViewer
I 7 - 202 Jmol OpenAstexViewer
J 7 - 202 Jmol OpenAstexViewer
3L2Y A 7 - 202 Jmol OpenAstexViewer
B 7 - 202 Jmol OpenAstexViewer
C 7 - 202 Jmol OpenAstexViewer
D 7 - 202 Jmol OpenAstexViewer
E 7 - 202 Jmol OpenAstexViewer
F 7 - 202 Jmol OpenAstexViewer
G 7 - 202 Jmol OpenAstexViewer
H 7 - 202 Jmol OpenAstexViewer
I 7 - 202 Jmol OpenAstexViewer
J 7 - 202 Jmol OpenAstexViewer
K 7 - 202 Jmol OpenAstexViewer
L 7 - 202 Jmol OpenAstexViewer
M 7 - 202 Jmol OpenAstexViewer
N 7 - 202 Jmol OpenAstexViewer
O 7 - 202 Jmol OpenAstexViewer
P 7 - 202 Jmol OpenAstexViewer
Q 7 - 202 Jmol OpenAstexViewer
R 7 - 202 Jmol OpenAstexViewer
S 7 - 202 Jmol OpenAstexViewer
T 7 - 202 Jmol OpenAstexViewer
3PVN A 7 - 202 Jmol OpenAstexViewer
B 7 - 202 Jmol OpenAstexViewer
C 7 - 202 Jmol OpenAstexViewer
D 7 - 202 Jmol OpenAstexViewer
E 7 - 202 Jmol OpenAstexViewer
F 7 - 202 Jmol OpenAstexViewer
G 7 - 202 Jmol OpenAstexViewer
H 7 - 202 Jmol OpenAstexViewer
I 7 - 202 Jmol OpenAstexViewer
J 7 - 202 Jmol OpenAstexViewer
K 7 - 202 Jmol OpenAstexViewer
L 7 - 202 Jmol OpenAstexViewer
M 7 - 202 Jmol OpenAstexViewer
N 7 - 202 Jmol OpenAstexViewer
O 7 - 202 Jmol OpenAstexViewer
P 7 - 202 Jmol OpenAstexViewer
Q 7 - 202 Jmol OpenAstexViewer
R 7 - 202 Jmol OpenAstexViewer
S 7 - 202 Jmol OpenAstexViewer
T 7 - 202 Jmol OpenAstexViewer
3PVO A 7 - 202 Jmol OpenAstexViewer
B 7 - 202 Jmol OpenAstexViewer
C 7 - 202 Jmol OpenAstexViewer
D 7 - 202 Jmol OpenAstexViewer
E 7 - 202 Jmol OpenAstexViewer
F 7 - 202 Jmol OpenAstexViewer
G 7 - 202 Jmol OpenAstexViewer
H 7 - 202 Jmol OpenAstexViewer
I 7 - 202 Jmol OpenAstexViewer
J 7 - 202 Jmol OpenAstexViewer
K 7 - 202 Jmol OpenAstexViewer
L 7 - 202 Jmol OpenAstexViewer
M 7 - 202 Jmol OpenAstexViewer
N 7 - 202 Jmol OpenAstexViewer
O 7 - 202 Jmol OpenAstexViewer
P 7 - 202 Jmol OpenAstexViewer
Q 7 - 202 Jmol OpenAstexViewer
R 7 - 202 Jmol OpenAstexViewer
S 7 - 202 Jmol OpenAstexViewer
T 7 - 202 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.