Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: AMBP_HUMAN (P02760)

Summary

This is the summary of UniProt entry AMBP_HUMAN (P02760).

Description: Protein AMBP
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 352 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
sig_p n/a 1 19
low_complexity n/a 2 18
Pfam Lipocalin 41 186
disorder n/a 185 186
disorder n/a 200 205
disorder n/a 211 212
disorder n/a 217 221
Pfam Kunitz_BPTI 230 282
Pfam Kunitz_BPTI 286 338

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P02760. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRSLGALLLL LSACLAVSAG PVPTPPDNIQ VQENFNISRI YGKWYNLAIG
50
51
STCPWLKKIM DRMTVSTLVL GEGATEAEIS MTSTRWRKGV CEETSGAYEK
100
101
TDTDGKFLYH KSKWNITMES YVVHTNYDEY AIFLTKKFSR HHGPTITAKL
150
151
YGRAPQLRET LLQDFRVVAQ GVGIPEDSIF TMADRGECVP GEQEPEPILI
200
201
PRVRRAVLPQ EEEGSGGGQL VTEVTKKEDS CQLGYSAGPC MGMTSRYFYN
250
251
GTSMACETFQ YGGCMGNGNN FVTEKECLQT CRTVAACNLP IVRGPCRAFI
300
301
QLWAFDAVKG KCVLFPYGGC QGNGNKFYSE KECREYCGVP GDGDEELLRF
350
351
SN                                                    
352
 

Show the unformatted sequence.

Checksums:
CRC64:BC001780094CBD06
MD5:b4fb18b904ac5b854c7994a3aadc1182

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Kunitz_BPTI 230 - 282 1BIK A 25 - 77 Jmol OpenAstexViewer
286 - 338 1BIK A 81 - 133 Jmol OpenAstexViewer
4U30 W 4 - 56 Jmol OpenAstexViewer
X 4 - 56 Jmol OpenAstexViewer
Y 4 - 56 Jmol OpenAstexViewer
Z 4 - 56 Jmol OpenAstexViewer
Lipocalin 41 - 186 3QKG A 22 - 167 Jmol OpenAstexViewer
4ES7 A 15 - 160 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.