Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
12  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: FRIL_HUMAN (P02792)

Summary

This is the summary of UniProt entry FRIL_HUMAN (P02792).

Description: Ferritin light chain
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 175 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam Ferritin 14 155
coiled_coil n/a 53 73
low_complexity n/a 96 107

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P02792. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSSQIRQNYS TDVEAAVNSL VNLYLQASYT YLSLGFYFDR DDVALEGVSH
50
51
FFRELAEEKR EGYERLLKMQ NQRGGRALFQ DIKKPAEDEW GKTPDAMKAA
100
101
MALEKKLNQA LLDLHALGSA RTDPHLCDFL ETHFLDEEVK LIKKMGDHLT
150
151
NLHRLGGPEA GLGEYLFERL TLKHD                           
175
 

Show the unformatted sequence.

Checksums:
CRC64:0DB98081FF976BC2
MD5:9597e7172639e4471c9e6dd510418bde

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ferritin 14 - 155 2FFX J 17 - 158 Show 3D Structure View in InterPro
2FG4 A 17 - 158 Show 3D Structure View in InterPro
2FG8 A 17 - 158 Show 3D Structure View in InterPro
B 17 - 158 Show 3D Structure View in InterPro
C 17 - 158 Show 3D Structure View in InterPro
D 17 - 158 Show 3D Structure View in InterPro
E 17 - 158 Show 3D Structure View in InterPro
F 17 - 158 Show 3D Structure View in InterPro
G 17 - 158 Show 3D Structure View in InterPro
H 17 - 158 Show 3D Structure View in InterPro
3KXU A 14 - 155 Show 3D Structure View in InterPro
5LG8 A 17 - 158 Show 3D Structure View in InterPro
6TR9 AAA 17 - 158 Show 3D Structure View in InterPro
6TS0 AAA 17 - 158 Show 3D Structure View in InterPro
6TS1 AAA 17 - 158 Show 3D Structure View in InterPro
6TSA AAA 17 - 158 Show 3D Structure View in InterPro
6TSF AAA 17 - 158 Show 3D Structure View in InterPro
6TSJ AAA 17 - 158 Show 3D Structure View in InterPro
6WX6 A 17 - 158 Show 3D Structure View in InterPro
B 17 - 158 Show 3D Structure View in InterPro
C 17 - 158 Show 3D Structure View in InterPro
D 17 - 158 Show 3D Structure View in InterPro
E 17 - 158 Show 3D Structure View in InterPro
F 17 - 158 Show 3D Structure View in InterPro
G 17 - 158 Show 3D Structure View in InterPro
H 17 - 158 Show 3D Structure View in InterPro
I 17 - 158 Show 3D Structure View in InterPro
J 17 - 158 Show 3D Structure View in InterPro
K 17 - 158 Show 3D Structure View in InterPro
L 17 - 158 Show 3D Structure View in InterPro
M 17 - 158 Show 3D Structure View in InterPro
N 17 - 158 Show 3D Structure View in InterPro
O 17 - 158 Show 3D Structure View in InterPro
P 17 - 158 Show 3D Structure View in InterPro
Q 17 - 158 Show 3D Structure View in InterPro
R 17 - 158 Show 3D Structure View in InterPro
S 17 - 158 Show 3D Structure View in InterPro
T 17 - 158 Show 3D Structure View in InterPro
U 17 - 158 Show 3D Structure View in InterPro
V 17 - 158 Show 3D Structure View in InterPro
W 17 - 158 Show 3D Structure View in InterPro
X 17 - 158 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;