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27  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: FRIH_HUMAN (P02794)

Summary

This is the summary of UniProt entry FRIH_HUMAN (P02794).

Description: Ferritin heavy chain EC=1.16.3.1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 183 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 3 9
disorder n/a 11 13
Pfam Ferritin 18 159
disorder n/a 67 70
disorder n/a 180 183

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P02794. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTTASTSQVR QNYHQDSEAA INRQINLELY ASYVYLSMSY YFDRDDVALK
50
51
NFAKYFLHQS HEEREHAEKL MKLQNQRGGR IFLQDIKKPD CDDWESGLNA
100
101
MECALHLEKN VNQSLLELHK LATDKNDPHL CDFIETHYLN EQVKAIKELG
150
151
DHVTNLRKMG APESGLAEYL FDKHTLGDSD NES                  
183
 

Show the unformatted sequence.

Checksums:
CRC64:FEF75640A29CCF56
MD5:0a9ad101e9d8a8996656b21f0dce6651

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ferritin 18 - 159 1FHA A 17 - 158 Jmol OpenAstexViewer
2CEI A 17 - 158 Jmol OpenAstexViewer
2CHI A 17 - 158 Jmol OpenAstexViewer
2CIH A 17 - 158 Jmol OpenAstexViewer
2CLU A 17 - 158 Jmol OpenAstexViewer
2CN6 A 17 - 158 Jmol OpenAstexViewer
2CN7 A 17 - 158 Jmol OpenAstexViewer
2FHA A 17 - 158 Jmol OpenAstexViewer
2IU2 A 17 - 158 Jmol OpenAstexViewer
2Z6M A 17 - 158 Jmol OpenAstexViewer
B 17 - 158 Jmol OpenAstexViewer
C 17 - 158 Jmol OpenAstexViewer
D 17 - 158 Jmol OpenAstexViewer
E 17 - 158 Jmol OpenAstexViewer
F 17 - 158 Jmol OpenAstexViewer
G 17 - 158 Jmol OpenAstexViewer
H 17 - 158 Jmol OpenAstexViewer
I 17 - 158 Jmol OpenAstexViewer
J 17 - 158 Jmol OpenAstexViewer
K 17 - 158 Jmol OpenAstexViewer
L 17 - 158 Jmol OpenAstexViewer
3AJO A 17 - 158 Jmol OpenAstexViewer
3AJP A 17 - 158 Jmol OpenAstexViewer
3AJQ A 17 - 158 Jmol OpenAstexViewer
3ERZ A 17 - 158 Jmol OpenAstexViewer
B 17 - 158 Jmol OpenAstexViewer
C 17 - 158 Jmol OpenAstexViewer
D 17 - 158 Jmol OpenAstexViewer
E 17 - 158 Jmol OpenAstexViewer
F 17 - 158 Jmol OpenAstexViewer
G 17 - 158 Jmol OpenAstexViewer
H 17 - 158 Jmol OpenAstexViewer
I 17 - 158 Jmol OpenAstexViewer
J 17 - 158 Jmol OpenAstexViewer
K 17 - 158 Jmol OpenAstexViewer
L 17 - 158 Jmol OpenAstexViewer
3ES3 A 17 - 158 Jmol OpenAstexViewer
4DYX A 17 - 158 Jmol OpenAstexViewer
4DYY A 17 - 158 Jmol OpenAstexViewer
4DYZ A 17 - 158 Jmol OpenAstexViewer
4DZ0 A 17 - 158 Jmol OpenAstexViewer
4OYN A 17 - 158 Jmol OpenAstexViewer
4Y08 A 17 - 158 Jmol OpenAstexViewer
4YKH A 17 - 158 Jmol OpenAstexViewer
4ZJK A 17 - 158 Jmol OpenAstexViewer
5CMQ A 17 - 158 Jmol OpenAstexViewer
5CMR A 17 - 158 Jmol OpenAstexViewer
5JKL A 17 - 158 Jmol OpenAstexViewer
B 17 - 158 Jmol OpenAstexViewer
C 17 - 158 Jmol OpenAstexViewer
D 17 - 158 Jmol OpenAstexViewer
E 17 - 158 Jmol OpenAstexViewer
F 17 - 158 Jmol OpenAstexViewer
G 17 - 158 Jmol OpenAstexViewer
H 17 - 158 Jmol OpenAstexViewer
I 17 - 158 Jmol OpenAstexViewer
J 17 - 158 Jmol OpenAstexViewer
K 17 - 158 Jmol OpenAstexViewer
L 17 - 158 Jmol OpenAstexViewer
5JKM A 17 - 158 Jmol OpenAstexViewer
B 17 - 158 Jmol OpenAstexViewer
C 17 - 158 Jmol OpenAstexViewer
D 17 - 158 Jmol OpenAstexViewer
E 17 - 158 Jmol OpenAstexViewer
F 17 - 158 Jmol OpenAstexViewer
G 17 - 158 Jmol OpenAstexViewer
H 17 - 158 Jmol OpenAstexViewer
I 17 - 158 Jmol OpenAstexViewer
J 17 - 158 Jmol OpenAstexViewer
K 17 - 158 Jmol OpenAstexViewer
L 17 - 158 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.