Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
11  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TOLC_ECOLI (P02930)

Summary

This is the summary of UniProt entry TOLC_ECOLI (P02930).

Description: Outer membrane protein TolC
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 493 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
sig_p n/a 1 22
low_complexity n/a 3 19
Pfam OEP 25 209
disorder n/a 229 234
Pfam OEP 231 427
disorder n/a 257 262
disorder n/a 265 266
disorder n/a 270 271
disorder n/a 278 279
disorder n/a 281 298
low_complexity n/a 350 364
disorder n/a 438 493

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P02930. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKKLLPILIG LSLSGFSSLS QAENLMQVYQ QARLSNPELR KSAADRDAAF
50
51
EKINEARSPL LPQLGLGADY TYSNGYRDAN GINSNATSAS LQLTQSIFDM
100
101
SKWRALTLQE KAAGIQDVTY QTDQQTLILN TATAYFNVLN AIDVLSYTQA
150
151
QKEAIYRQLD QTTQRFNVGL VAITDVQNAR AQYDTVLANE VTARNNLDNA
200
201
VEQLRQITGN YYPELAALNV ENFKTDKPQP VNALLKEAEK RNLSLLQARL
250
251
SQDLAREQIR QAQDGHLPTL DLTASTGISD TSYSGSKTRG AAGTQYDDSN
300
301
MGQNKVGLSF SLPIYQGGMV NSQVKQAQYN FVGASEQLES AHRSVVQTVR
350
351
SSFNNINASI SSINAYKQAV VSAQSSLDAM EAGYSVGTRT IVDVLDATTT
400
401
LYNAKQELAN ARYNYLINQL NIKSALGTLN EQDLLALNNA LSKPVSTNPE
450
451
NVAPQTPEQN AIADGYAPDS PAPVVQQTSA RTTTSNGHNP FRN       
493
 

Show the unformatted sequence.

Checksums:
CRC64:6F97B4C62A848FE1
MD5:43c25df8e3937e9cf2d501de8338fc94

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
OEP 231 - 427 1EK9 A 209 - 405 Jmol OpenAstexViewer
B 209 - 405 Jmol OpenAstexViewer
C 209 - 405 Jmol OpenAstexViewer
1TQQ A 209 - 405 Jmol OpenAstexViewer
B 209 - 405 Jmol OpenAstexViewer
C 209 - 405 Jmol OpenAstexViewer
2VDD A 231 - 427 Jmol OpenAstexViewer
B 231 - 427 Jmol OpenAstexViewer
C 231 - 427 Jmol OpenAstexViewer
2VDE A 231 - 427 Jmol OpenAstexViewer
B 231 - 427 Jmol OpenAstexViewer
C 231 - 427 Jmol OpenAstexViewer
2WMZ A 209 - 405 Jmol OpenAstexViewer
B 209 - 405 Jmol OpenAstexViewer
C 209 - 405 Jmol OpenAstexViewer
2XMN A 209 - 405 Jmol OpenAstexViewer
B 209 - 405 Jmol OpenAstexViewer
C 209 - 405 Jmol OpenAstexViewer
5NG5 C 209 - 405 Jmol OpenAstexViewer
F 209 - 405 Jmol OpenAstexViewer
I 209 - 405 Jmol OpenAstexViewer
5NIK A 209 - 405 Jmol OpenAstexViewer
B 209 - 405 Jmol OpenAstexViewer
C 209 - 405 Jmol OpenAstexViewer
5NIL A 209 - 405 Jmol OpenAstexViewer
B 209 - 405 Jmol OpenAstexViewer
C 209 - 405 Jmol OpenAstexViewer
5O66 A 209 - 405 Jmol OpenAstexViewer
B 209 - 405 Jmol OpenAstexViewer
C 209 - 405 Jmol OpenAstexViewer
5V5S A 209 - 405 Jmol OpenAstexViewer
B 209 - 405 Jmol OpenAstexViewer
C 209 - 405 Jmol OpenAstexViewer
25 - 209 1EK9 A 3 - 187 Jmol OpenAstexViewer
B 3 - 187 Jmol OpenAstexViewer
C 3 - 187 Jmol OpenAstexViewer
1TQQ A 3 - 187 Jmol OpenAstexViewer
B 3 - 187 Jmol OpenAstexViewer
C 3 - 187 Jmol OpenAstexViewer
2VDD A 25 - 209 Jmol OpenAstexViewer
B 25 - 209 Jmol OpenAstexViewer
C 25 - 209 Jmol OpenAstexViewer
2VDE A 25 - 209 Jmol OpenAstexViewer
B 25 - 209 Jmol OpenAstexViewer
C 25 - 209 Jmol OpenAstexViewer
2WMZ A 3 - 187 Jmol OpenAstexViewer
B 3 - 187 Jmol OpenAstexViewer
C 3 - 187 Jmol OpenAstexViewer
2XMN A 3 - 187 Jmol OpenAstexViewer
B 3 - 187 Jmol OpenAstexViewer
C 3 - 187 Jmol OpenAstexViewer
5NG5 C 3 - 187 Jmol OpenAstexViewer
F 3 - 187 Jmol OpenAstexViewer
I 3 - 187 Jmol OpenAstexViewer
5NIK A 3 - 187 Jmol OpenAstexViewer
B 3 - 187 Jmol OpenAstexViewer
C 3 - 187 Jmol OpenAstexViewer
5NIL A 3 - 187 Jmol OpenAstexViewer
B 3 - 187 Jmol OpenAstexViewer
C 3 - 187 Jmol OpenAstexViewer
5O66 A 3 - 187 Jmol OpenAstexViewer
B 3 - 187 Jmol OpenAstexViewer
C 3 - 187 Jmol OpenAstexViewer
5V5S A 3 - 187 Jmol OpenAstexViewer
B 3 - 187 Jmol OpenAstexViewer
C 3 - 187 Jmol OpenAstexViewer