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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RPB1_DROME (P04052)

Summary

This is the summary of UniProt entry RPB1_DROME (P04052).

Description: DNA-directed RNA polymerase II subunit RPB1 EC=2.7.7.6
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
Length: 1887 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 7
Pfam RNA_pol_Rpb1_1 11 346
disorder n/a 33 34
disorder n/a 50 55
disorder n/a 121 127
disorder n/a 155 177
disorder n/a 190 195
low_complexity n/a 242 257
disorder n/a 315 330
disorder n/a 332 334
Pfam RNA_pol_Rpb1_2 348 513
disorder n/a 497 500
disorder n/a 504 506
disorder n/a 508 510
disorder n/a 512 514
Pfam RNA_pol_Rpb1_3 516 684
disorder n/a 597 601
disorder n/a 603 610
coiled_coil n/a 691 718
Pfam RNA_pol_Rpb1_4 708 815
disorder n/a 719 724
disorder n/a 748 749
Pfam RNA_pol_Rpb1_5 822 1419
Pfam RNA_pol_Rpb1_6 888 1071
coiled_coil n/a 927 961
Pfam RNA_pol_Rpb1_7 1156 1291
coiled_coil n/a 1254 1274
disorder n/a 1262 1265
disorder n/a 1493 1494
low_complexity n/a 1495 1508
disorder n/a 1497 1498
disorder n/a 1503 1507
disorder n/a 1509 1514
disorder n/a 1520 1574
low_complexity n/a 1529 1544
low_complexity n/a 1546 1567
low_complexity n/a 1566 1591
disorder n/a 1579 1606
low_complexity n/a 1588 1610
disorder n/a 1609 1647
low_complexity n/a 1626 1650
disorder n/a 1649 1653
disorder n/a 1656 1660
disorder n/a 1662 1666
low_complexity n/a 1665 1738
disorder n/a 1668 1694
disorder n/a 1696 1701
disorder n/a 1703 1887
low_complexity n/a 1734 1749
low_complexity n/a 1755 1775
low_complexity n/a 1788 1803
low_complexity n/a 1795 1813
low_complexity n/a 1832 1849
low_complexity n/a 1860 1881

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P04052. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSTPTDSKAP LRQVKRVQFG ILSPDEIRRM SVTEGGVQFA ETMEGGRPKL
50
51
GGLMDPRQGV IDRTSRCQTC AGNMTECPGH FGHIDLAKPV FHIGFITKTI
100
101
KILRCVCFYC SKMLVSPHNP KIKEIVMKSR GQPRKRLAYV YDLCKGKTIC
150
151
EGGEDMDLTK ENQQPDPNKK PGHGGCGHYQ PSIRRTGLDL TAEWKHQNED
200
201
SQEKKIVVSA ERVWEILKHI TDEECFILGM DPKYARPDWM IVTVLPVPPL
250
251
AVRPAVVMFG AAKNQDDLTH KLSDIIKANN ELRKNEASGA AAHVIQENIK
300
301
MLQFHVATLV DNDMPGMPRA MQKSGKPLKA IKARLKGKEG RIRGNLMGKR
350
351
VDFSARTVIT PDPNLRIDQV GVPRSIAQNL TFPELVTPFN IDRMQELVRR
400
401
GNSQYPGAKY IVRDNGERID LRFHPKSSDL HLQCGYKVER HLRDDDLVIF
450
451
NRQPTLHKMS MMGHRVKVLP WSTFRMNLSC TSPYNADFDG DEMNLHVPQS
500
501
METRAEVENI HITPRQIITP QANKPVMGIV QDTLTAVRKM TKRDVFITRE
550
551
QVMNLLMFLP TWDAKMPQPC ILKPRPLWTG KQIFSLIIPG NVNMIRTHST
600
601
HPDEEDEGPY KWISPGDTKV MVEHGELIMG ILCKKSLGTS AGSLLHICFL
650
651
ELGHDIAGRF YGNIQTVINN WLLFEGHSIG IGDTIADPQT YNEIQQAIKK
700
701
AKDDVINVIQ KAHNMELEPT PGNTLRQTFE NKVNRILNDA RDKTGGSAKK
750
751
SLTEYNNLKA MVVSGSKGSN INISQVIACV GQQNVEGKRI PYGFRKRTLP
800
801
HFIKDDYGPE SRGFVENSYL AGLTPSEFYF HAMGGREGLI DTAVKTAETG
850
851
YIQRRLIKAM ESVMVNYDGT VRNSVGQLIQ LRYGEDGLCG ELVEFQNMPT
900
901
VKLSNKSFEK RFKFDWSNER LMKKVFTDDV IKEMTDSSEA IQELEAEWDR
950
951
LVSDRDSLRQ IFPNGESKVV LPCNLQRMIW NVQKIFHINK RLPTDLSPIR
1000
1001
VIKGVKTLLE RCVIVTGNDR ISKQANENAT LLFQCLIRST LCTKYVSEEF
1050
1051
RLSTEAFEWL VGEIETRFQQ AQANPGEMVG ALAAQSLGEP ATQMTLNTFH
1100
1101
FAGVSSKNVT LGVPRLKEII NISKKPKAPS LTVFLTGGAA RDAEKAKNVL
1150
1151
CRLEHTTLRK VTANTAIYYD PDPQRTVISE DQEFVNVYYE MPDFDPTRIS
1200
1201
PWLLRIELDR KRMTDKKLTM EQIAEKINVG FGEDLNCIFN DDNADKLVLR
1250
1251
IRIMNNEENK FQDEDEAVDK MEDDMFLRCI EANMLSDMTL QGIEAIGKVY
1300
1301
MHLPQTDSKK RIVITETGEF KAIGEWLLET DGTSMMKVLS ERDVDPIRTS
1350
1351
SNDICEIFQV LGIEAVRKSV EKEMNAVLQF YGLYVNYRHL ALLCDVMTAK
1400
1401
GHLMAITRHG INRQDTGALM RCSFEETVDV LMDAAAHAET DPMRGVSENI
1450
1451
IMGQLPKMGT GCFDLLLDAE KCRFGIEIPN TLGNSMLGGA AMFIGGGSTP
1500
1501
SMTPPMTPWA NCNTPRYFSP PGHVSAMTPG GPSFSPSAAS DASGMSPSWS
1550
1551
PAHPGSSPSS PGPSMSPYFP ASPSVSPSYS PTSPNYTASS PGGASPNYSP
1600
1601
SSPNYSPTSP LYASPRYAST TPNFNPQSTG YSPSSSGYSP TSPVYSPTVQ
1650
1651
FQSSPSFAGS GSNIYSPGNA YSPSSSNYSP NSPSYSPTSP SYSPSSPSYS
1700
1701
PTSPCYSPTS PSYSPTSPNY TPVTPSYSPT SPNYSASPQY SPASPAYSQT
1750
1751
GVKYSPTSPT YSPPSPSYDG SPGSPQYTPG SPQYSPASPK YSPTSPLYSP
1800
1801
SSPQHSPSNQ YSPTGSTYSA TSPRYSPNMS IYSPSSTKYS PTSPTYTPTA
1850
1851
RNYSPTSPMY SPTAPSHYSP TSPAYSPSSP TFEESED              
1887
 

Show the unformatted sequence.

Checksums:
CRC64:4EC68C7708A167A3
MD5:c749514bf9bc0cb81f3aa0aa1b2fb007

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;