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4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HSPB1_HUMAN (P04792)

Summary

This is the summary of UniProt entry HSPB1_HUMAN (P04792).

Description: Heat shock protein beta-1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 205 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
low_complexity n/a 58 71
Pfam HSP20 87 184
disorder n/a 114 126
disorder n/a 129 132
disorder n/a 148 180
disorder n/a 182 205

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P04792. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTERRVPFSL LRGPSWDPFR DWYPHSRLFD QAFGLPRLPE EWSQWLGGSS
50
51
WPGYVRPLPP AAIESPAVAA PAYSRALSRQ LSSGVSEIRH TADRWRVSLD
100
101
VNHFAPDELT VKTKDGVVEI TGKHEERQDE HGYISRCFTR KYTLPPGVDP
150
151
TQVSSSLSPE GTLTVEAPMP KLATQSNEIT IPVTFESRAQ LGGPEAAKSD
200
201
ETAAK                                                 
205
 

Show the unformatted sequence.

Checksums:
CRC64:1B4DC44A6F6606D5
MD5:ecfdc628b02afd7205471106883edf08

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
HSP20 179 - 184 4MJH B 179 - 184 Jmol OpenAstexViewer
D 179 - 184 Jmol OpenAstexViewer
87 - 169 4MJH C 87 - 169 Jmol OpenAstexViewer
87 - 170 4MJH A 87 - 170 Jmol OpenAstexViewer
87 - 176 2N3J A 87 - 176 Jmol OpenAstexViewer
B 87 - 176 Jmol OpenAstexViewer
90 - 170 3Q9Q A 90 - 170 Jmol OpenAstexViewer
90 - 171 3Q9P A 90 - 171 Jmol OpenAstexViewer
94 - 170 3Q9Q B 94 - 170 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.