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58  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: H2A1B_HUMAN (P04908)

Summary

This is the summary of UniProt entry H2A1B_HUMAN (P04908).

Description: Histone H2A type 1-B/E
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 130 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 19
low_complexity n/a 1 22
Pfam Histone 2 91
disorder n/a 81 82
Pfam Histone_H2A_C 92 126
disorder n/a 119 130

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P04908. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSGRGKQGGK ARAKAKTRSS RAGLQFPVGR VHRLLRKGNY SERVGAGAPV
50
51
YLAAVLEYLT AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGR
100
101
VTIAQGGVLP NIQAVLLPKK TESHHKAKGK                      
130
 

Show the unformatted sequence.

Checksums:
CRC64:9CFE6184B2CC89F5
MD5:eb9a1e9f1c207300757bcd20505f7ab5

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Histone 10 - 91 5GSE G 9 - 90 Jmol OpenAstexViewer
11 - 91 5JRG G 10 - 90 Jmol OpenAstexViewer
12 - 91 2CV5 C 11 - 90 Jmol OpenAstexViewer
3AFA C 11 - 90 Jmol OpenAstexViewer
3AYW C 11 - 90 Jmol OpenAstexViewer
3AZE C 11 - 90 Jmol OpenAstexViewer
3AZF C 11 - 90 Jmol OpenAstexViewer
3AZG C 11 - 90 Jmol OpenAstexViewer
3AZI C 11 - 90 Jmol OpenAstexViewer
3AZJ C 11 - 90 Jmol OpenAstexViewer
3AZK C 11 - 90 Jmol OpenAstexViewer
3AZL C 11 - 90 Jmol OpenAstexViewer
3AZN C 11 - 90 Jmol OpenAstexViewer
3X1V G 11 - 90 Jmol OpenAstexViewer
4YM6 C 11 - 90 Jmol OpenAstexViewer
5B0Z C 11 - 90 Jmol OpenAstexViewer
5B24 C 11 - 90 Jmol OpenAstexViewer
5B32 C 11 - 90 Jmol OpenAstexViewer
5CPI C 11 - 90 Jmol OpenAstexViewer
5GTC C 11 - 90 Jmol OpenAstexViewer
5GXQ C 11 - 90 Jmol OpenAstexViewer
5X7X C 11 - 90 Jmol OpenAstexViewer
6BUZ C 12 - 91 Jmol OpenAstexViewer
G 12 - 91 Jmol OpenAstexViewer
13 - 91 3W96 C 12 - 90 Jmol OpenAstexViewer
3WKJ C 12 - 90 Jmol OpenAstexViewer
3WTP C 12 - 90 Jmol OpenAstexViewer
5GSE M 12 - 90 Jmol OpenAstexViewer
5GTC G 12 - 90 Jmol OpenAstexViewer
5JRG C 12 - 90 Jmol OpenAstexViewer
5VEY A 101 - 179 Jmol OpenAstexViewer
14 - 91 3AZH C 13 - 90 Jmol OpenAstexViewer
3AZM C 13 - 90 Jmol OpenAstexViewer
3W97 C 13 - 90 Jmol OpenAstexViewer
3W98 C 13 - 90 Jmol OpenAstexViewer
3X1V C 13 - 90 Jmol OpenAstexViewer
5AV5 C 13 - 90 Jmol OpenAstexViewer
5AV6 C 13 - 90 Jmol OpenAstexViewer
5AV8 C 13 - 90 Jmol OpenAstexViewer
5AV9 C 13 - 90 Jmol OpenAstexViewer
5AVB C 13 - 90 Jmol OpenAstexViewer
5AVC C 13 - 90 Jmol OpenAstexViewer
5B2I C 13 - 90 Jmol OpenAstexViewer
5B2J C 13 - 90 Jmol OpenAstexViewer
5B31 C 13 - 90 Jmol OpenAstexViewer
5CPK C 13 - 90 Jmol OpenAstexViewer
6ETX K 13 - 90 Jmol OpenAstexViewer
15 - 91 3A6N C 14 - 90 Jmol OpenAstexViewer
3AV1 C 14 - 90 Jmol OpenAstexViewer
3AV2 C 14 - 90 Jmol OpenAstexViewer
3AZK G 14 - 90 Jmol OpenAstexViewer
3AZL G 14 - 90 Jmol OpenAstexViewer
3W99 C 14 - 90 Jmol OpenAstexViewer
3WTP G 14 - 90 Jmol OpenAstexViewer
3X1S C 14 - 90 Jmol OpenAstexViewer
4YM5 C 14 - 90 Jmol OpenAstexViewer
4Z5T C 14 - 90 Jmol OpenAstexViewer
5AV5 G 14 - 90 Jmol OpenAstexViewer
5AV6 G 14 - 90 Jmol OpenAstexViewer
5AV8 G 14 - 90 Jmol OpenAstexViewer
5AV9 G 14 - 90 Jmol OpenAstexViewer
5AVB G 14 - 90 Jmol OpenAstexViewer
5AVC G 14 - 90 Jmol OpenAstexViewer
5AY8 C 14 - 90 Jmol OpenAstexViewer
5B0Y C 14 - 90 Jmol OpenAstexViewer
5B2I G 14 - 90 Jmol OpenAstexViewer
5B2J G 14 - 90 Jmol OpenAstexViewer
5B40 C 14 - 90 Jmol OpenAstexViewer
5CPJ C 14 - 90 Jmol OpenAstexViewer
5X7X G 14 - 90 Jmol OpenAstexViewer
5XF3 C 14 - 90 Jmol OpenAstexViewer
G 14 - 90 Jmol OpenAstexViewer
5XF4 C 14 - 90 Jmol OpenAstexViewer
G 14 - 90 Jmol OpenAstexViewer
5XF5 C 14 - 90 Jmol OpenAstexViewer
G 14 - 90 Jmol OpenAstexViewer
6ETX O 14 - 90 Jmol OpenAstexViewer
16 - 91 2CV5 G 15 - 90 Jmol OpenAstexViewer
3A6N G 15 - 90 Jmol OpenAstexViewer
3AFA G 15 - 90 Jmol OpenAstexViewer
3AN2 G 15 - 90 Jmol OpenAstexViewer
3AV1 G 15 - 90 Jmol OpenAstexViewer
3AV2 G 15 - 90 Jmol OpenAstexViewer
3AZE G 15 - 90 Jmol OpenAstexViewer
3AZF G 15 - 90 Jmol OpenAstexViewer
3AZG G 15 - 90 Jmol OpenAstexViewer
3AZH G 15 - 90 Jmol OpenAstexViewer
3AZI G 15 - 90 Jmol OpenAstexViewer
3AZJ G 15 - 90 Jmol OpenAstexViewer
3AZM G 15 - 90 Jmol OpenAstexViewer
3AZN G 15 - 90 Jmol OpenAstexViewer
3W98 G 15 - 90 Jmol OpenAstexViewer
3WKJ G 15 - 90 Jmol OpenAstexViewer
3X1S G 15 - 90 Jmol OpenAstexViewer
4YM6 G 15 - 90 Jmol OpenAstexViewer
4Z5T G 15 - 90 Jmol OpenAstexViewer
5AY8 G 15 - 90 Jmol OpenAstexViewer
5B0Y G 15 - 90 Jmol OpenAstexViewer
5B0Z G 15 - 90 Jmol OpenAstexViewer
5B24 G 15 - 90 Jmol OpenAstexViewer
5B40 G 15 - 90 Jmol OpenAstexViewer
5CPI G 15 - 90 Jmol OpenAstexViewer
5CPJ G 15 - 90 Jmol OpenAstexViewer
5CPK G 15 - 90 Jmol OpenAstexViewer
5GXQ G 15 - 90 Jmol OpenAstexViewer
17 - 91 3AN2 C 16 - 90 Jmol OpenAstexViewer
3AYW G 16 - 90 Jmol OpenAstexViewer
3W96 G 16 - 90 Jmol OpenAstexViewer
3W97 G 16 - 90 Jmol OpenAstexViewer
4YM5 G 16 - 90 Jmol OpenAstexViewer
5GSE C 16 - 90 Jmol OpenAstexViewer
18 - 91 3W99 G 17 - 90 Jmol OpenAstexViewer
2 - 91 2RVQ C 1 - 90 Jmol OpenAstexViewer
Histone_H2A_C 92 - 106 5VEY A 180 - 194 Jmol OpenAstexViewer
92 - 111 3AZJ C 91 - 110 Jmol OpenAstexViewer
G 91 - 110 Jmol OpenAstexViewer
92 - 113 3AN2 C 91 - 112 Jmol OpenAstexViewer
92 - 115 3AN2 G 91 - 114 Jmol OpenAstexViewer
92 - 117 3WTP G 91 - 116 Jmol OpenAstexViewer
92 - 118 5B40 C 91 - 117 Jmol OpenAstexViewer
5CPJ G 91 - 117 Jmol OpenAstexViewer
5GSE C 91 - 117 Jmol OpenAstexViewer
G 91 - 117 Jmol OpenAstexViewer
M 91 - 117 Jmol OpenAstexViewer
6BUZ C 92 - 118 Jmol OpenAstexViewer
G 92 - 118 Jmol OpenAstexViewer
92 - 119 2CV5 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3A6N C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AFA C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AV1 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AV2 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AYW C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AZE C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AZF C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AZG C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AZH C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AZI C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AZK C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AZL C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AZM C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3AZN C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3W96 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3W97 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3W98 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3W99 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3WKJ C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3WTP C 91 - 118 Jmol OpenAstexViewer
3X1S C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
3X1V C 91 - 118 Jmol OpenAstexViewer
4YM5 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
4YM6 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
4Z5T C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5AV5 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5AV6 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5AV8 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5AV9 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5AVB C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5AVC C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5AY8 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5B0Y C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5B0Z C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5B24 C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5B2I C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5B2J C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5B32 C 91 - 118 Jmol OpenAstexViewer
5B40 G 91 - 118 Jmol OpenAstexViewer
5CPI C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5CPJ C 91 - 118 Jmol OpenAstexViewer
5CPK C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5GTC C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5GXQ C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5JRG C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
5X7X C 91 - 118 Jmol OpenAstexViewer
G 91 - 118 Jmol OpenAstexViewer
6ETX K 91 - 118 Jmol OpenAstexViewer
O 91 - 118 Jmol OpenAstexViewer
92 - 120 3X1V G 91 - 119 Jmol OpenAstexViewer
5B31 C 91 - 119 Jmol OpenAstexViewer
5XF3 C 91 - 119 Jmol OpenAstexViewer
G 91 - 119 Jmol OpenAstexViewer
5XF4 C 91 - 119 Jmol OpenAstexViewer
G 91 - 119 Jmol OpenAstexViewer
5XF5 C 91 - 119 Jmol OpenAstexViewer
G 91 - 119 Jmol OpenAstexViewer
92 - 126 2RVQ C 91 - 125 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.