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11  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: FUMC_ECOLI (P05042)

Summary

This is the summary of UniProt entry FUMC_ECOLI (P05042).

Description: Fumarate hydratase class II {ECO:0000255|HAMAP-Rule:MF_00743, ECO:0000303|PubMed:3282546}
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 467 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 10
Pfam Lyase_1 12 342
disorder n/a 15 18
disorder n/a 32 33
disorder n/a 75 77
disorder n/a 92 97
disorder n/a 104 109
disorder n/a 121 141
low_complexity n/a 222 237
disorder n/a 317 318
disorder n/a 320 323
Pfam FumaraseC_C 408 461
low_complexity n/a 419 430
low_complexity n/a 432 441
disorder n/a 465 466

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P05042. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNTVRSEKDS MGAIDVPADK LWGAQTQRSL EHFRISTEKM PTSLIHALAL
50
51
TKRAAAKVNE DLGLLSEEKA SAIRQAADEV LAGQHDDEFP LAIWQTGSGT
100
101
QSNMNMNEVL ANRASELLGG VRGMERKVHP NDDVNKSQSS NDVFPTAMHV
150
151
AALLALRKQL IPQLKTLTQT LNEKSRAFAD IVKIGRTHLQ DATPLTLGQE
200
201
ISGWVAMLEH NLKHIEYSLP HVAELALGGT AVGTGLNTHP EYARRVADEL
250
251
AVITCAPFVT APNKFEALAT CDALVQAHGA LKGLAASLMK IANDVRWLAS
300
301
GPRCGIGEIS IPENEPGSSI MPGKVNPTQC EALTMLCCQV MGNDVAINMG
350
351
GASGNFELNV FRPMVIHNFL QSVRLLADGM ESFNKHCAVG IEPNRERINQ
400
401
LLNESLMLVT ALNTHIGYDK AAEIAKKAHK EGLTLKAAAL ALGYLSEAEF
450
451
DSWVRPEQMV GSMKAGR                                    
467
 

Show the unformatted sequence.

Checksums:
CRC64:3D67E3C0F0FDF40B
MD5:ba9ea4f2a2bede4d365c5a32e4fd7009

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
FumaraseC_C 408 - 459 1FUO A 408 - 459 Jmol OpenAstexViewer
B 408 - 459 Jmol OpenAstexViewer
1FUP A 408 - 459 Jmol OpenAstexViewer
B 408 - 459 Jmol OpenAstexViewer
1FUQ A 408 - 459 Jmol OpenAstexViewer
B 408 - 459 Jmol OpenAstexViewer
1FUR A 408 - 459 Jmol OpenAstexViewer
B 408 - 459 Jmol OpenAstexViewer
1KQ7 A 408 - 459 Jmol OpenAstexViewer
B 408 - 459 Jmol OpenAstexViewer
2FUS A 408 - 459 Jmol OpenAstexViewer
B 408 - 459 Jmol OpenAstexViewer
408 - 460 1YFE A 408 - 460 Jmol OpenAstexViewer
408 - 461 6NZ9 A 408 - 461 Jmol OpenAstexViewer
B 408 - 461 Jmol OpenAstexViewer
6NZA A 408 - 461 Jmol OpenAstexViewer
B 408 - 461 Jmol OpenAstexViewer
6NZB A 408 - 461 Jmol OpenAstexViewer
B 408 - 461 Jmol OpenAstexViewer
6NZC A 408 - 461 Jmol OpenAstexViewer
B 408 - 461 Jmol OpenAstexViewer
Lyase_1 12 - 342 1FUO A 12 - 342 Jmol OpenAstexViewer
B 12 - 342 Jmol OpenAstexViewer
1FUP A 12 - 342 Jmol OpenAstexViewer
B 12 - 342 Jmol OpenAstexViewer
1FUQ A 12 - 342 Jmol OpenAstexViewer
B 12 - 342 Jmol OpenAstexViewer
1FUR A 12 - 342 Jmol OpenAstexViewer
B 12 - 342 Jmol OpenAstexViewer
1KQ7 A 12 - 342 Jmol OpenAstexViewer
B 12 - 342 Jmol OpenAstexViewer
1YFE A 12 - 342 Jmol OpenAstexViewer
2FUS A 12 - 342 Jmol OpenAstexViewer
B 12 - 342 Jmol OpenAstexViewer
6NZ9 A 12 - 342 Jmol OpenAstexViewer
B 12 - 342 Jmol OpenAstexViewer
6NZA A 12 - 342 Jmol OpenAstexViewer
B 12 - 342 Jmol OpenAstexViewer
6NZB A 12 - 342 Jmol OpenAstexViewer
B 12 - 342 Jmol OpenAstexViewer
6NZC A 12 - 342 Jmol OpenAstexViewer
B 12 - 342 Jmol OpenAstexViewer