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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: NOT2_YEAST (P06100)

Summary

This is the summary of UniProt entry NOT2_YEAST (P06100).

Description: General negative regulator of transcription subunit 2
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
View Pfam proteome data.
Length: 191 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam NOT2_3_5 53 190

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P06100. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEKFGLKALV PLLKLEDKEL SSTYDHSMTL GADLSSMLYS LGIPRDSQDH
50
51
RVLDTFQSPW AETSRSEVEP RFFTPESFTN IPGVLQSTVT PPCFNSIQND
100
101
QQRVALFQDE TLFFLFYKHP GTVIQELTYL ELRKRNWRYH KTLKAWLTKD
150
151
PMMEPIVSAD GLSERGSYVF FDPQRWEKCQ RDFLLFYNAI M         
191
 

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Checksums:
CRC64:7D0B69657F791371
MD5:5bb331672b45edb7ac0b7d9d0e2258fd

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
NOT2_3_5 53 - 190 4BY6 B 53 - 190 Jmol OpenAstexViewer
E 53 - 190 Jmol OpenAstexViewer