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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: DLD_ECOLI (P06149)

Summary

This is the summary of UniProt entry DLD_ECOLI (P06149).

Description: Quinone-dependent D-lactate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_02092, ECO:0000305}
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 571 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam FAD_binding_4 46 186
disorder n/a 83 86
disorder n/a 206 209
low_complexity n/a 206 218
disorder n/a 213 217
Pfam Lact-deh-memb 278 567
low_complexity n/a 435 440
disorder n/a 545 566
disorder n/a 569 571

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P06149. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSSMTTTDNK AFLNELARLV GSSHLLTDPA KTARYRKGFR SGQGDALAVV
50
51
FPGSLLELWR VLKACVTADK IILMQAANTG LTEGSTPNGN DYDRDVVIIS
100
101
TLRLDKLHVL GKGEQVLAYP GTTLYSLEKA LKPLGREPHS VIGSSCIGAS
150
151
VIGGICNNSG GSLVQRGPAY TEMSLFARIN EDGKLTLVNH LGIDLGETPE
200
201
QILSKLDDDR IKDDDVRHDG RHAHDYDYVH RVRDIEADTP ARYNADPDRL
250
251
FESSGCAGKL AVFAVRLDTF EAEKNQQVFY IGTNQPEVLT EIRRHILANF
300
301
ENLPVAGEYM HRDIYDIAEK YGKDTFLMID KLGTDKMPFF FNLKGRTDAM
350
351
LEKVKFFRPH FTDRAMQKFG HLFPSHLPPR MKNWRDKYEH HLLLKMAGDG
400
401
VGEAKSWLVD YFKQAEGDFF VCTPEEGSKA FLHRFAAAGA AIRYQAVHSD
450
451
EVEDILALDI ALRRNDTEWY EHLPPEIDSQ LVHKLYYGHF MCYVFHQDYI
500
501
VKKGVDVHAL KEQMLELLQQ RGAQYPAEHN VGHLYKAPET LQKFYRENDP
550
551
TNSMNPGIGK TSKRKNWQEV E                               
571
 

Show the unformatted sequence.

Checksums:
CRC64:77FB2C467CB4389F
MD5:a5e840582b686cd8ce1e1d13ef92c2f3

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
FAD_binding_4 46 - 186 1F0X A 46 - 186 Jmol OpenAstexViewer
B 1046 - 1186 Jmol OpenAstexViewer
Lact-deh-memb 278 - 567 1F0X A 278 - 567 Jmol OpenAstexViewer
B 1278 - 1567 Jmol OpenAstexViewer