|Description:||Chymotrypsin-like elastase family member 2A EC=18.104.22.168|
Homo sapiens (Human)
(NCBI taxonomy ID
View Pfam proteome data.
|Length:||269 amino acids|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
This image shows the arrangement of the Pfam domains that we found on this sequence. Clicking on a domain will take you to the page describing that Pfam entry. The table below gives the domain boundaries for each of the domains. More...
E-values are based on searching the Pfam-A family against UniProtKB 2018_04 using hmmsearch.
Download the data used to generate the domain graphic in JSON format.
or the data used to generate the graphic in JSON format.
|Source||Domain||Start||End||Gathering threshold (bits)||Score (bits)||E-value|
or domain scores.
This is the amino acid sequence of the UniProt sequence database entry with the accession P08217. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
MIRTLLLSTL VAGALSCGDP TYPPYVTRVV GGEEARPNSW PWQVSLQYSS
NGKWYHTCGG SLIANSWVLT AAHCISSSRT YRVGLGRHNL YVAESGSLAV
SVSKIVVHKD WNSNQISKGN DIALLKLANP VSLTDKIQLA CLPPAGTILP
NNYPCYVTGW GRLQTNGAVP DVLQQGRLLV VDYATCSSSA WWGSSVKTSM
ICAGGDGVIS SCNGDSGGPL NCQASDGRWQ VHGIVSFGSR LGCNYYHKPS
the unformatted sequence.
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.