Summary
This is the summary of UniProt entry INHBA_HUMAN (P08476).
Description: | Inhibin beta A chain |
Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
Length: | 426 amino acids |
Reference Proteome: |
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Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
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Source | Domain | Start | End |
---|---|---|---|
sig_p | n/a | 1 | 20 |
disorder | n/a | 26 | 31 |
disorder | n/a | 42 | 43 |
Pfam | TGFb_propeptide | 46 | 295 |
disorder | n/a | 111 | 112 |
disorder | n/a | 171 | 174 |
disorder | n/a | 179 | 194 |
disorder | n/a | 197 | 198 |
low_complexity | n/a | 257 | 285 |
disorder | n/a | 258 | 302 |
disorder | n/a | 304 | 309 |
Pfam | TGF_beta | 320 | 425 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P08476. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
Sequence: | 1
MPLLWLRGFL LASCWIIVRS SPTPGSEGHS AAPDCPSCAL AALPKDVPNS
50 51
QPEMVEAVKK HILNMLHLKK RPDVTQPVPK AALLNAIRKL HVGKVGENGY
100 101
VEIEDDIGRR AEMNELMEQT SEIITFAESG TARKTLHFEI SKEGSDLSVV
150 151
ERAEVWLFLK VPKANRTRTK VTIRLFQQQK HPQGSLDTGE EAEEVGLKGE
200 201
RSELLLSEKV VDARKSTWHV FPVSSSIQRL LDQGKSSLDV RIACEQCQES
250 251
GASLVLLGKK KKKEEEGEGK KKGGGEGGAG ADEEKEQSHR PFLMLQARQS
300 301
EDHPHRRRRR GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC
350 351
EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS
400 401
MLYYDDGQNI IKKDIQNMIV EECGCS
426
Show the unformatted sequence. |
Checksums: |
CRC64:201CDEDF99CB6919
MD5:b0f0d7c08526ba669da1df28620cfa7c
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.