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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: GM4D_ECOLI (P0AC88)

Summary

This is the summary of UniProt entry GM4D_ECOLI (P0AC88).

Description: GDP-mannose 4,6-dehydratase {ECO:0000255|HAMAP-Rule:MF_00955}
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 373 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam GDP_Man_Dehyd 6 346

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P0AC88. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSKVALITGV TGQDGSYLAE FLLEKGYEVH GIKRRASSFN TERVDHIYQD
50
51
PHTCNPKFHL HYGDLSDTSN LTRILREVQP DEVYNLGAMS HVAVSFESPE
100
101
YTADVDAMGT LRLLEAIRFL GLEKKTRFYQ ASTSELYGLV QEIPQKETTP
150
151
FYPRSPYAVA KLYAYWITVN YRESYGMYAC NGILFNHESP RRGETFVTRK
200
201
ITRAIANIAQ GLESCLYLGN MDSLRDWGHA KDYVKMQWMM LQQEQPEDFV
250
251
IATGVQYSVR QFVEMAAAQL GIKLRFEGTG VEEKGIVVSV TGHDAPGVKP
300
301
GDVIIAVDPR YFRPAEVETL LGDPTKAHEK LGWKPEITLR EMVSEMVAND
350
351
LEAAKKHSLL KSHGYDVAIA LES                             
373
 

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Checksums:
CRC64:1A9BA2A7C566DE11
MD5:d6a0ba6bed90c6f7d54a08c3fbbcd213

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
GDP_Man_Dehyd 6 - 346 1DB3 A 5 - 345 Jmol OpenAstexViewer