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42  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CRP_ECOLI (P0ACJ8)

Summary

This is the summary of UniProt entry CRP_ECOLI (P0ACJ8).

Description: cAMP-activated global transcriptional regulator CRP
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 210 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam cNMP_binding 21 110
Pfam HTH_Crp_2 142 207
disorder n/a 160 164

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P0ACJ8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVLGKPQTDP TLEWFLSHCH IHKYPSKSTL IHQGEKAETL YYIVKGSVAV
50
51
LIKDEEGKEM ILSYLNQGDF IGELGLFEEG QERSAWVRAK TACEVAEISY
100
101
KKFRQLIQVN PDILMRLSAQ MARRLQVTSE KVGNLAFLDV TGRIAQTLLN
150
151
LAKQPDAMTH PDGMQIKITR QEIGQIVGCS RETVGRILKM LEDQNLISAH
200
201
GKTIVVYGTR                                            
210
 

Show the unformatted sequence.

Checksums:
CRC64:DCBC24FA46C61B3D
MD5:9a58754a5c561c0784b75360a962f090

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
cNMP_binding 21 - 110 1CGP A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
1G6N A 20 - 109 Jmol OpenAstexViewer
B 320 - 409 Jmol OpenAstexViewer
1HW5 A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
1I5Z A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
1I6X A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
1J59 A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
1LB2 A 20 - 109 Jmol OpenAstexViewer
1O3Q A 20 - 109 Jmol OpenAstexViewer
1O3R A 20 - 109 Jmol OpenAstexViewer
1O3S A 20 - 109 Jmol OpenAstexViewer
1O3T A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
1RUN A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
1RUO A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
1ZRC A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
1ZRD A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
1ZRE A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
1ZRF A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
2CGP A 20 - 109 Jmol OpenAstexViewer
2GZW A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
C 20 - 109 Jmol OpenAstexViewer
D 20 - 109 Jmol OpenAstexViewer
2WC2 A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
3FWE A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
3HIF A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
C 20 - 109 Jmol OpenAstexViewer
D 20 - 109 Jmol OpenAstexViewer
E 20 - 109 Jmol OpenAstexViewer
F 20 - 109 Jmol OpenAstexViewer
3IYD G 20 - 109 Jmol OpenAstexViewer
H 20 - 109 Jmol OpenAstexViewer
3KCC A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
3N4M A 20 - 109 Jmol OpenAstexViewer
3QOP A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
3RDI A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
3ROU A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
3RPQ A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
3RYP A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
3RYR A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
4BH9 A 20 - 109 Jmol OpenAstexViewer
4BHP A 20 - 109 Jmol OpenAstexViewer
4FT8 A 20 - 109 Jmol OpenAstexViewer
B 20 - 109 Jmol OpenAstexViewer
4HZF A 21 - 110 Jmol OpenAstexViewer
B 21 - 110 Jmol OpenAstexViewer
4I01 A 21 - 110 Jmol OpenAstexViewer
B 21 - 110 Jmol OpenAstexViewer
4I02 A 21 - 110 Jmol OpenAstexViewer
B 21 - 110 Jmol OpenAstexViewer
C 21 - 110 Jmol OpenAstexViewer
D 21 - 110 Jmol OpenAstexViewer
E 21 - 110 Jmol OpenAstexViewer
F 21 - 110 Jmol OpenAstexViewer
4I09 A 21 - 110 Jmol OpenAstexViewer
B 21 - 110 Jmol OpenAstexViewer
4I0A A 21 - 110 Jmol OpenAstexViewer
B 21 - 110 Jmol OpenAstexViewer
4I0B A 21 - 110 Jmol OpenAstexViewer
B 21 - 110 Jmol OpenAstexViewer
4R8H A 21 - 110 Jmol OpenAstexViewer
B 21 - 110 Jmol OpenAstexViewer
5CIZ A 20 - 109 Jmol OpenAstexViewer
HTH_Crp_2 142 - 204 2GZW B 141 - 203 Jmol OpenAstexViewer
142 - 206 1CGP A 141 - 205 Jmol OpenAstexViewer
B 141 - 205 Jmol OpenAstexViewer
1HW5 B 141 - 205 Jmol OpenAstexViewer
1J59 B 141 - 205 Jmol OpenAstexViewer
1O3T B 141 - 205 Jmol OpenAstexViewer
1RUN B 141 - 205 Jmol OpenAstexViewer
142 - 207 1G6N A 141 - 206 Jmol OpenAstexViewer
B 441 - 506 Jmol OpenAstexViewer
1HW5 A 141 - 206 Jmol OpenAstexViewer
1I5Z A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
1I6X A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
1J59 A 141 - 206 Jmol OpenAstexViewer
1LB2 A 141 - 206 Jmol OpenAstexViewer
1O3Q A 141 - 206 Jmol OpenAstexViewer
1O3R A 141 - 206 Jmol OpenAstexViewer
1O3S A 141 - 206 Jmol OpenAstexViewer
1O3T A 141 - 206 Jmol OpenAstexViewer
1RUN A 141 - 206 Jmol OpenAstexViewer
1RUO A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
1ZRC A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
1ZRD A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
1ZRE A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
1ZRF A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
2CGP A 141 - 206 Jmol OpenAstexViewer
2GZW A 141 - 206 Jmol OpenAstexViewer
C 141 - 206 Jmol OpenAstexViewer
D 141 - 206 Jmol OpenAstexViewer
2WC2 A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
3FWE A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
3HIF A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
C 141 - 206 Jmol OpenAstexViewer
D 141 - 206 Jmol OpenAstexViewer
E 141 - 206 Jmol OpenAstexViewer
F 141 - 206 Jmol OpenAstexViewer
3IYD G 141 - 206 Jmol OpenAstexViewer
H 141 - 206 Jmol OpenAstexViewer
3KCC A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
3N4M A 141 - 206 Jmol OpenAstexViewer
3QOP A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
3RDI A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
3ROU A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
3RPQ A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
3RYP A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
3RYR A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
4BH9 A 141 - 206 Jmol OpenAstexViewer
4BHP A 141 - 206 Jmol OpenAstexViewer
4FT8 A 141 - 206 Jmol OpenAstexViewer
B 141 - 206 Jmol OpenAstexViewer
4HZF A 142 - 207 Jmol OpenAstexViewer
B 142 - 207 Jmol OpenAstexViewer
4I01 A 142 - 207 Jmol OpenAstexViewer
B 142 - 207 Jmol OpenAstexViewer
4I02 A 142 - 207 Jmol OpenAstexViewer
B 142 - 207 Jmol OpenAstexViewer
C 142 - 207 Jmol OpenAstexViewer
D 142 - 207 Jmol OpenAstexViewer
E 142 - 207 Jmol OpenAstexViewer
F 142 - 207 Jmol OpenAstexViewer
4I09 A 142 - 207 Jmol OpenAstexViewer
B 142 - 207 Jmol OpenAstexViewer
4I0A A 142 - 207 Jmol OpenAstexViewer
B 142 - 207 Jmol OpenAstexViewer
4I0B A 142 - 207 Jmol OpenAstexViewer
B 142 - 207 Jmol OpenAstexViewer
4R8H A 142 - 207 Jmol OpenAstexViewer
B 142 - 207 Jmol OpenAstexViewer
5CIZ A 141 - 206 Jmol OpenAstexViewer