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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: KPYK1_ECOLI (P0AD61)

Summary

This is the summary of UniProt entry KPYK1_ECOLI (P0AD61).

Description: Pyruvate kinase I EC=2.7.1.40
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 470 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam PK 1 345
disorder n/a 285 289
disorder n/a 296 297
Pfam PK_C 356 468

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P0AD61. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKKTKIVCTI GPKTESEEML AKMLDAGMNV MRLNFSHGDY AEHGQRIQNL
50
51
RNVMSKTGKT AAILLDTKGP EIRTMKLEGG NDVSLKAGQT FTFTTDKSVI
100
101
GNSEMVAVTY EGFTTDLSVG NTVLVDDGLI GMEVTAIEGN KVICKVLNNG
150
151
DLGENKGVNL PGVSIALPAL AEKDKQDLIF GCEQGVDFVA ASFIRKRSDV
200
201
IEIREHLKAH GGENIHIISK IENQEGLNNF DEILEASDGI MVARGDLGVE
250
251
IPVEEVIFAQ KMMIEKCIRA RKVVITATQM LDSMIKNPRP TRAEAGDVAN
300
301
AILDGTDAVM LSGESAKGKY PLEAVSIMAT ICERTDRVMN SRLEFNNDNR
350
351
KLRITEAVCR GAVETAEKLD APLIVVATQG GKSARAVRKY FPDATILALT
400
401
TNEKTAHQLV LSKGVVPQLV KEITSTDDFY RLGKELALQS GLAHKGDVVV
450
451
MVSGALVPSG TTNTASVHVL                                 
470
 

Show the unformatted sequence.

Checksums:
CRC64:E29BF01B90327D8B
MD5:b364e47c26991e4e943e4d21553d6140

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PK 1 - 344 1E0T A 1 - 344 Jmol OpenAstexViewer
B 1 - 344 Jmol OpenAstexViewer
C 1 - 344 Jmol OpenAstexViewer
D 1 - 344 Jmol OpenAstexViewer
1E0U A 1 - 344 Jmol OpenAstexViewer
B 1 - 344 Jmol OpenAstexViewer
C 1 - 344 Jmol OpenAstexViewer
D 1 - 344 Jmol OpenAstexViewer
1PKY A 1 - 344 Jmol OpenAstexViewer
B 1 - 344 Jmol OpenAstexViewer
C 1 - 344 Jmol OpenAstexViewer
D 1 - 344 Jmol OpenAstexViewer
PK_C 356 - 468 1E0T A 356 - 468 Jmol OpenAstexViewer
B 356 - 468 Jmol OpenAstexViewer
C 356 - 468 Jmol OpenAstexViewer
D 356 - 468 Jmol OpenAstexViewer
1E0U A 356 - 468 Jmol OpenAstexViewer
B 356 - 468 Jmol OpenAstexViewer
C 356 - 468 Jmol OpenAstexViewer
D 356 - 468 Jmol OpenAstexViewer
1PKY A 356 - 468 Jmol OpenAstexViewer
B 356 - 468 Jmol OpenAstexViewer
C 356 - 468 Jmol OpenAstexViewer
D 356 - 468 Jmol OpenAstexViewer