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4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GYRA_ECOLI (P0AES4)

Summary

This is the summary of UniProt entry GYRA_ECOLI (P0AES4).

Description: DNA gyrase subunit A {ECO:0000255|HAMAP-Rule:MF_01897}
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 875 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam DNA_topoisoIV 32 507
low_complexity n/a 354 365
low_complexity n/a 468 482
coiled_coil n/a 471 491
low_complexity n/a 496 510
Pfam DNA_gyraseA_C 538 585
Pfam DNA_gyraseA_C 588 638
Pfam DNA_gyraseA_C 645 689
Pfam DNA_gyraseA_C 692 739
Pfam DNA_gyraseA_C 743 790
disorder n/a 756 759
Pfam DNA_gyraseA_C 793 840
disorder n/a 835 875
low_complexity n/a 858 874

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P0AES4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSDLAREITP VNIEEELKSS YLDYAMSVIV GRALPDVRDG LKPVHRRVLY
50
51
AMNVLGNDWN KAYKKSARVV GDVIGKYHPH GDSAVYDTIV RMAQPFSLRY
100
101
MLVDGQGNFG SIDGDSAAAM RYTEIRLAKI AHELMADLEK ETVDFVDNYD
150
151
GTEKIPDVMP TKIPNLLVNG SSGIAVGMAT NIPPHNLTEV INGCLAYIDD
200
201
EDISIEGLME HIPGPDFPTA AIINGRRGIE EAYRTGRGKV YIRARAEVEV
250
251
DAKTGRETII VHEIPYQVNK ARLIEKIAEL VKEKRVEGIS ALRDESDKDG
300
301
MRIVIEVKRD AVGEVVLNNL YSQTQLQVSF GINMVALHHG QPKIMNLKDI
350
351
IAAFVRHRRE VVTRRTIFEL RKARDRAHIL EALAVALANI DPIIELIRHA
400
401
PTPAEAKTAL VANPWQLGNV AAMLERAGDD AARPEWLEPE FGVRDGLYYL
450
451
TEQQAQAILD LRLQKLTGLE HEKLLDEYKE LLDQIAELLR ILGSADRLME
500
501
VIREELELVR EQFGDKRRTE ITANSADINL EDLITQEDVV VTLSHQGYVK
550
551
YQPLSEYEAQ RRGGKGKSAA RIKEEDFIDR LLVANTHDHI LCFSSRGRVY
600
601
SMKVYQLPEA TRGARGRPIV NLLPLEQDER ITAILPVTEF EEGVKVFMAT
650
651
ANGTVKKTVL TEFNRLRTAG KVAIKLVDGD ELIGVDLTSG EDEVMLFSAE
700
701
GKVVRFKESS VRAMGCNTTG VRGIRLGEGD KVVSLIVPRG DGAILTATQN
750
751
GYGKRTAVAE YPTKSRATKG VISIKVTERN GLVVGAVQVD DCDQIMMITD
800
801
AGTLVRTRVS EISIVGRNTQ GVILIRTAED ENVVGLQRVA EPVDEEDLDT
850
851
IDGSAAEGDD EIAPEVDVDD EPEEE                           
875
 

Show the unformatted sequence.

Checksums:
CRC64:3FD5BD52A5969069
MD5:76463a0cc647d9eaf9e912ca32648522

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
DNA_gyraseA_C 538 - 585 1ZI0 A 538 - 585 Jmol OpenAstexViewer
B 538 - 585 Jmol OpenAstexViewer
588 - 638 1ZI0 A 588 - 638 Jmol OpenAstexViewer
B 588 - 638 Jmol OpenAstexViewer
645 - 689 1ZI0 A 645 - 689 Jmol OpenAstexViewer
B 645 - 689 Jmol OpenAstexViewer
692 - 739 1ZI0 A 692 - 739 Jmol OpenAstexViewer
B 692 - 739 Jmol OpenAstexViewer
743 - 790 1ZI0 A 743 - 790 Jmol OpenAstexViewer
B 743 - 790 Jmol OpenAstexViewer
793 - 840 1ZI0 A 793 - 840 Jmol OpenAstexViewer
B 793 - 840 Jmol OpenAstexViewer
DNA_topoisoIV 32 - 507 1AB4 A 32 - 507 Jmol OpenAstexViewer
3NUH A 32 - 507 Jmol OpenAstexViewer
363 - 494 1X75 A 363 - 494 Jmol OpenAstexViewer
B 363 - 494 Jmol OpenAstexViewer