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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: ODO1_ECOLI (P0AFG3)

Summary

This is the summary of UniProt entry ODO1_ECOLI (P0AFG3).

Description: 2-oxoglutarate dehydrogenase E1 component EC=1.2.4.2
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 933 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam 2-oxogl_dehyd_N 12 52
disorder n/a 52 53
Pfam E1_dh 207 516
disorder n/a 282 283
disorder n/a 464 475
Pfam Transket_pyr 589 785
disorder n/a 639 642
Pfam OxoGdeHyase_C 788 930

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P0AFG3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQNSALKAWL DSSYLSGANQ SWIEQLYEDF LTDPDSVDAN WRSTFQQLPG
50
51
TGVKPDQFHS QTREYFRRLA KDASRYSSTI SDPDTNVKQV KVLQLINAYR
100
101
FRGHQHANLD PLGLWQQDKV ADLDPSFHDL TEADFQETFN VGSFASGKET
150
151
MKLGELLEAL KQTYCGPIGA EYMHITSTEE KRWIQQRIES GRATFNSEEK
200
201
KRFLSELTAA EGLERYLGAK FPGAKRFSLE GGDALIPMLK EMIRHAGNSG
250
251
TREVVLGMAH RGRLNVLVNV LGKKPQDLFD EFAGKHKEHL GTGDVKYHMG
300
301
FSSDFQTDGG LVHLALAFNP SHLEIVSPVV IGSVRARLDR LDEPSSNKVL
350
351
PITIHGDAAV TGQGVVQETL NMSKARGYEV GGTVRIVINN QVGFTTSNPL
400
401
DARSTPYCTD IGKMVQAPIF HVNADDPEAV AFVTRLALDF RNTFKRDVFI
450
451
DLVCYRRHGH NEADEPSATQ PLMYQKIKKH PTPRKIYADK LEQEKVATLE
500
501
DATEMVNLYR DALDAGDCVV AEWRPMNMHS FTWSPYLNHE WDEEYPNKVE
550
551
MKRLQELAKR ISTVPEAVEM QSRVAKIYGD RQAMAAGEKL FDWGGAENLA
600
601
YATLVDEGIP VRLSGEDSGR GTFFHRHAVI HNQSNGSTYT PLQHIHNGQG
650
651
AFRVWDSVLS EEAVLAFEYG YATAEPRTLT IWEAQFGDFA NGAQVVIDQF
700
701
ISSGEQKWGR MCGLVMLLPH GYEGQGPEHS SARLERYLQL CAEQNMQVCV
750
751
PSTPAQVYHM LRRQALRGMR RPLVVMSPKS LLRHPLAVSS LEELANGTFL
800
801
PAIGEIDELD PKGVKRVVMC SGKVYYDLLE QRRKNNQHDV AIVRIEQLYP
850
851
FPHKAMQEVL QQFAHVKDFV WCQEEPLNQG AWYCSQHHFR EVIPFGASLR
900
901
YAGRPASASP AVGYMSVHQK QQQDLVNDAL NVE                  
933
 

Show the unformatted sequence.

Checksums:
CRC64:EAEF8429EC31E749
MD5:5cf06ce62b9e2618a775454fd37dbb54

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
E1_dh 207 - 516 2JGD A 207 - 516 Jmol OpenAstexViewer
B 207 - 516 Jmol OpenAstexViewer
OxoGdeHyase_C 788 - 930 2JGD A 788 - 930 Jmol OpenAstexViewer
B 788 - 930 Jmol OpenAstexViewer
Transket_pyr 589 - 785 2JGD A 589 - 785 Jmol OpenAstexViewer
B 589 - 785 Jmol OpenAstexViewer