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22  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: FTSY_ECOLI (P10121)

Summary

This is the summary of UniProt entry FTSY_ECOLI (P10121).

Description: Signal recognition particle receptor FtsY {ECO:0000255|HAMAP-Rule:MF_00920}
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 497 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 11 189
low_complexity n/a 58 76
low_complexity n/a 84 106
low_complexity n/a 130 188
coiled_coil n/a 138 158
Pfam SRP54_N 207 275
low_complexity n/a 224 236
Pfam SRP54 293 494

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P10121. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAKEKKRGFF SWLGFGQKEQ TPEKETEVQN EQPVVEEIVQ AQEPVKASEQ
50
51
AVEEQPQAHT EAEAETFAAD VVEVTEQVAE SEKAQPEAEV VAQPEPVVEE
100
101
TPEPVAIERE ELPLPEDVNA EAVSPEEWQA EAETVEIVEA AEEEAAKEEI
150
151
TDEELETALA AEAAEEAVMV VPPAEEEQPV EEIAQEQEKP TKEGFFARLK
200
201
RSLLKTKENL GSGFISLFRG KKIDDDLFEE LEEQLLIADV GVETTRKIIT
250
251
NLTEGASRKQ LRDAEALYGL LKEEMGEILA KVDEPLNVEG KAPFVILMVG
300
301
VNGVGKTTTI GKLARQFEQQ GKSVMLAAGD TFRAAAVEQL QVWGQRNNIP
350
351
VIAQHTGADS ASVIFDAIQA AKARNIDVLI ADTAGRLQNK SHLMEELKKI
400
401
VRVMKKLDVE APHEVMLTID ASTGQNAVSQ AKLFHEAVGL TGITLTKLDG
450
451
TAKGGVIFSV ADQFGIPIRY IGVGERIEDL RPFKADDFIE ALFARED   
497
 

Show the unformatted sequence.

Checksums:
CRC64:EBE640072B5D1021
MD5:233bc2755a82238e8bb6ecca7feb7762

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
SRP54 293 - 483 5GAD l 293 - 483 Show 3D Structure View in InterPro
293 - 493 6FQD B 293 - 493 Show 3D Structure View in InterPro
293 - 494 1FTS A 293 - 494 Show 3D Structure View in InterPro
2QY9 A 293 - 494 Show 3D Structure View in InterPro
2XXA B 98 - 299 Show 3D Structure View in InterPro
D 98 - 299 Show 3D Structure View in InterPro
2YHS A 293 - 494 Show 3D Structure View in InterPro
3ZN8 D 293 - 494 Show 3D Structure View in InterPro
4C7O B 99 - 300 Show 3D Structure View in InterPro
D 99 - 300 Show 3D Structure View in InterPro
5NCO l 99 - 300 Show 3D Structure View in InterPro
5NIY A 293 - 494 Show 3D Structure View in InterPro
6CQP A 293 - 494 Show 3D Structure View in InterPro
B 293 - 494 Show 3D Structure View in InterPro
6CS8 A 293 - 494 Show 3D Structure View in InterPro
B 293 - 494 Show 3D Structure View in InterPro
6CVD A 293 - 494 Show 3D Structure View in InterPro
B 293 - 494 Show 3D Structure View in InterPro
6DLX A 293 - 494 Show 3D Structure View in InterPro
B 293 - 494 Show 3D Structure View in InterPro
6FQD A 293 - 494 Show 3D Structure View in InterPro
6N5I A 293 - 494 Show 3D Structure View in InterPro
B 293 - 494 Show 3D Structure View in InterPro
6N5J A 293 - 494 Show 3D Structure View in InterPro
B 293 - 494 Show 3D Structure View in InterPro
6N6N A 293 - 494 Show 3D Structure View in InterPro
B 293 - 494 Show 3D Structure View in InterPro
6N9B A 293 - 494 Show 3D Structure View in InterPro
B 293 - 494 Show 3D Structure View in InterPro
6NC1 A 293 - 494 Show 3D Structure View in InterPro
B 293 - 494 Show 3D Structure View in InterPro
6NC4 A 293 - 494 Show 3D Structure View in InterPro
B 293 - 494 Show 3D Structure View in InterPro
SRP54_N 207 - 275 1FTS A 207 - 275 Show 3D Structure View in InterPro
2QY9 A 207 - 275 Show 3D Structure View in InterPro
2YHS A 207 - 275 Show 3D Structure View in InterPro
3ZN8 D 207 - 275 Show 3D Structure View in InterPro
5NIY A 207 - 275 Show 3D Structure View in InterPro
6CQP A 207 - 275 Show 3D Structure View in InterPro
B 207 - 275 Show 3D Structure View in InterPro
6CS8 A 207 - 275 Show 3D Structure View in InterPro
B 207 - 275 Show 3D Structure View in InterPro
6CVD A 207 - 275 Show 3D Structure View in InterPro
B 207 - 275 Show 3D Structure View in InterPro
6DLX A 207 - 275 Show 3D Structure View in InterPro
B 207 - 275 Show 3D Structure View in InterPro
6N5I A 207 - 275 Show 3D Structure View in InterPro
B 207 - 275 Show 3D Structure View in InterPro
6N5J A 207 - 275 Show 3D Structure View in InterPro
B 207 - 275 Show 3D Structure View in InterPro
6N6N A 207 - 275 Show 3D Structure View in InterPro
B 207 - 275 Show 3D Structure View in InterPro
6N9B A 207 - 275 Show 3D Structure View in InterPro
B 207 - 275 Show 3D Structure View in InterPro
6NC1 A 207 - 275 Show 3D Structure View in InterPro
B 207 - 275 Show 3D Structure View in InterPro
6NC4 A 207 - 275 Show 3D Structure View in InterPro
B 207 - 275 Show 3D Structure View in InterPro
215 - 275 2XXA B 20 - 80 Show 3D Structure View in InterPro
D 20 - 80 Show 3D Structure View in InterPro
221 - 272 6FPR A 3 - 54 Show 3D Structure View in InterPro
221 - 275 6FQD A 221 - 275 Show 3D Structure View in InterPro
B 221 - 275 Show 3D Structure View in InterPro
222 - 275 6FPR B 4 - 57 Show 3D Structure View in InterPro
224 - 275 4C7O B 30 - 81 Show 3D Structure View in InterPro
D 30 - 81 Show 3D Structure View in InterPro
5NCO l 30 - 81 Show 3D Structure View in InterPro
225 - 275 6FPK A 225 - 275 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;