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7  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SECA_ECOLI (P10408)

Summary

This is the summary of UniProt entry SECA_ECOLI (P10408).

Description: Protein translocase subunit SecA
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 901 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam SecA_DEAD 6 402
Pfam SecA_PP_bind 231 358
disorder n/a 256 262
disorder n/a 347 348
disorder n/a 565 575
disorder n/a 609 610
Pfam SecA_SW 617 830
disorder n/a 834 859
coiled_coil n/a 837 857
low_complexity n/a 854 872
disorder n/a 862 875
disorder n/a 877 888
Pfam SEC-C 881 899
disorder n/a 890 891

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P10408. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLIKLLTKVF GSRNDRTLRR MRKVVNIINA MEPEMEKLSD EELKGKTAEF
50
51
RARLEKGEVL ENLIPEAFAV VREASKRVFG MRHFDVQLLG GMVLNERCIA
100
101
EMRTGEGKTL TATLPAYLNA LTGKGVHVVT VNDYLAQRDA ENNRPLFEFL
150
151
GLTVGINLPG MPAPAKREAY AADITYGTNN EYGFDYLRDN MAFSPEERVQ
200
201
RKLHYALVDE VDSILIDEAR TPLIISGPAE DSSEMYKRVN KIIPHLIRQE
250
251
KEDSETFQGE GHFSVDEKSR QVNLTERGLV LIEELLVKEG IMDEGESLYS
300
301
PANIMLMHHV TAALRAHALF TRDVDYIVKD GEVIIVDEHT GRTMQGRRWS
350
351
DGLHQAVEAK EGVQIQNENQ TLASITFQNY FRLYEKLAGM TGTADTEAFE
400
401
FSSIYKLDTV VVPTNRPMIR KDLPDLVYMT EAEKIQAIIE DIKERTAKGQ
450
451
PVLVGTISIE KSELVSNELT KAGIKHNVLN AKFHANEAAI VAQAGYPAAV
500
501
TIATNMAGRG TDIVLGGSWQ AEVAALENPT AEQIEKIKAD WQVRHDAVLE
550
551
AGGLHIIGTE RHESRRIDNQ LRGRSGRQGD AGSSRFYLSM EDALMRIFAS
600
601
DRVSGMMRKL GMKPGEAIEH PWVTKAIANA QRKVESRNFD IRKQLLEYDD
650
651
VANDQRRAIY SQRNELLDVS DVSETINSIR EDVFKATIDA YIPPQSLEEM
700
701
WDIPGLQERL KNDFDLDLPI AEWLDKEPEL HEETLRERIL AQSIEVYQRK
750
751
EEVVGAEMMR HFEKGVMLQT LDSLWKEHLA AMDYLRQGIH LRGYAQKDPK
800
801
QEYKRESFSM FAAMLESLKY EVISTLSKVQ VRMPEEVEEL EQQRRMEAER
850
851
LAQMQQLSHQ DDDSAAAAAL AAQTGERKVG RNDPCPCGSG KKYKQCHGRL
900
901
Q                                                     
901
 

Show the unformatted sequence.

Checksums:
CRC64:683D66DD4305DBC2
MD5:1baad8fe077050f7097e1f3d00a93ace

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
SEC-C 881 - 899 1TM6 A 2 - 20 Jmol OpenAstexViewer
SecA_DEAD 11 - 402 2FSI B 11 - 402 Jmol OpenAstexViewer
3BXZ A 11 - 402 Jmol OpenAstexViewer
B 11 - 402 Jmol OpenAstexViewer
12 - 402 2FSF B 12 - 402 Jmol OpenAstexViewer
13 - 402 2FSF A 13 - 402 Jmol OpenAstexViewer
2FSG B 13 - 402 Jmol OpenAstexViewer
2FSH A 13 - 402 Jmol OpenAstexViewer
B 13 - 402 Jmol OpenAstexViewer
2FSI A 13 - 402 Jmol OpenAstexViewer
16 - 402 2FSG A 16 - 402 Jmol OpenAstexViewer
9 - 402 2VDA A 9 - 402 Jmol OpenAstexViewer
SecA_PP_bind 231 - 232 2FSH A 231 - 232 Jmol OpenAstexViewer
2FSI A 231 - 232 Jmol OpenAstexViewer
231 - 313 2FSF B 231 - 313 Jmol OpenAstexViewer
2FSH B 231 - 313 Jmol OpenAstexViewer
231 - 317 2FSG B 231 - 317 Jmol OpenAstexViewer
231 - 318 2FSI B 231 - 318 Jmol OpenAstexViewer
231 - 358 2VDA A 231 - 358 Jmol OpenAstexViewer
SecA_SW 617 - 830 2FSF A 617 - 830 Jmol OpenAstexViewer
B 617 - 830 Jmol OpenAstexViewer
2FSG A 617 - 830 Jmol OpenAstexViewer
B 617 - 830 Jmol OpenAstexViewer
2FSH A 617 - 830 Jmol OpenAstexViewer
B 617 - 830 Jmol OpenAstexViewer
2FSI A 617 - 830 Jmol OpenAstexViewer
B 617 - 830 Jmol OpenAstexViewer
2VDA A 617 - 830 Jmol OpenAstexViewer