Summary
This is the summary of UniProt entry ESTD_HUMAN (P10768).
Description: | S-formylglutathione hydrolase EC=3.1.2.12 EC=3.1.1.56 |
Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
Length: | 282 amino acids |
Reference Proteome: |
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Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
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Source | Domain | Start | End |
---|---|---|---|
Pfam | Esterase | 23 | 275 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P10768. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
Sequence: | 1
MALKQISSNK CFGGLQKVFE HDSVELNCKM KFAVYLPPKA ETGKCPALYW
50 51
LSGLTCTEQN FISKSGYHQS ASEHGLVVIA PDTSPRGCNI KGEDESWDFG
100 101
TGAGFYVDAT EDPWKTNYRM YSYVTEELPQ LINANFPVDP QRMSIFGHSM
150 151
GGHGALICAL KNPGKYKSVS AFAPICNPVL CPWGKKAFSG YLGTDQSKWK
200 201
AYDATHLVKS YPGSQLDILI DQGKDDQFLL DGQLLPDNFI AACTEKKIPV
250 251
VFRLQEGYDH SYYFIATFIT DHIRHHAKYL NA
282
Show the unformatted sequence. |
Checksums: |
CRC64:BFC20D5FA2BB0DCE
MD5:834269140f549c1e77107a9fc2165b8a
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
---|---|---|---|---|---|
Esterase | 23 - 275 | 3FCX | A | 23 - 275 | Jmol OpenAstexViewer |
B | 23 - 275 | Jmol OpenAstexViewer |
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.