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36  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RPA1_YEAST (P10964)

Summary

This is the summary of UniProt entry RPA1_YEAST (P10964).

Description: DNA-directed RNA polymerase I subunit RPA190 EC=2.7.7.6
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
Length: 1664 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam RNA_pol_Rpb1_1 8 471
disorder n/a 154 169
disorder n/a 204 211
disorder n/a 280 304
disorder n/a 309 312
disorder n/a 371 374
coiled_coil n/a 396 416
disorder n/a 448 454
Pfam RNA_pol_Rpb1_2 473 653
disorder n/a 528 532
disorder n/a 534 535
disorder n/a 558 565
disorder n/a 568 569
disorder n/a 572 575
disorder n/a 592 593
disorder n/a 599 602
disorder n/a 629 646
low_complexity n/a 640 652
disorder n/a 648 652
Pfam RNA_pol_Rpb1_3 656 833
disorder n/a 656 657
disorder n/a 661 662
disorder n/a 858 867
Pfam RNA_pol_Rpb1_4 863 982
disorder n/a 869 870
disorder n/a 875 879
Pfam RNA_pol_Rpb1_5 989 1611
low_complexity n/a 1095 1110
low_complexity n/a 1273 1287
disorder n/a 1277 1279
disorder n/a 1282 1284
coiled_coil n/a 1299 1319
disorder n/a 1308 1309
disorder n/a 1338 1446
low_complexity n/a 1399 1423
coiled_coil n/a 1425 1445

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P10964. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDISKPVGSE ITSVDFGILT AKEIRNLSAK QITNPTVLDN LGHPVSGGLY
50
51
DLALGAFLRN LCSTCGLDEK FCPGHQGHIE LPVPCYNPLF FNQLYIYLRA
100
101
SCLFCHHFRL KSVEVHRYAC KLRLLQYGLI DESYKLDEIT LGSLNSSMYT
150
151
DDEAIEDNED EMDGEGSKQS KDISSTLLNE LKSKRSEYVD MAIAKALSDG
200
201
RTTERGSFTA TVNDERKKLV HEFHKKLLSR GKCDNCGMFS PKFRKDGFTK
250
251
IFETALNEKQ ITNNRVKGFI RQDMIKKQKQ AKKLDGSNEA SANDEESFDV
300
301
GRNPTTRPKT GSTYILSTEV KNILDTVFRK EQCVLQYVFH SRPNLSRKLV
350
351
KADSFFMDVL VVPPTRFRLP SKLGEEVHEN SQNQLLSKVL TTSLLIRDLN
400
401
DDLSKLQKDK VSLEDRRVIF SRLMNAFVTI QNDVNAFIDS TKAQGRTSGK
450
451
VPIPGVKQAL EKKEGLFRKH MMGKRVNYAA RSVISPDPNI ETNEIGVPPV
500
501
FAVKLTYPEP VTAYNIAELR QAVINGPDKW PGATQIQNED GSLVSLIGMS
550
551
VEQRKALANQ LLTPSSNVST HTLNKKVYRH IKNRDVVLMN RQPTLHKASM
600
601
MGHKVRVLPN EKTLRLHYAN TGAYNADFDG DEMNMHFPQN ENARAEALNL
650
651
ANTDSQYLTP TSGSPVRGLI QDHISAGVWL TSKDSFFTRE QYQQYIYGCI
700
701
RPEDGHTTRS KIVTLPPTIF KPYPLWTGKQ IITTVLLNVT PPDMPGINLI
750
751
SKNKIKNEYW GKGSLENEVL FKDGALLCGI LDKSQYGASK YGIVHSLHEV
800
801
YGPEVAAKVL SVLGRLFTNY ITATAFTCGM DDLRLTAEGN KWRTDILKTS
850
851
VDTGREAAAE VTNLDKDTPA DDPELLKRLQ EILRDNNKSG ILDAVTSSKV
900
901
NAITSQVVSK CVPDGTMKKF PCNSMQAMAL SGAKGSNVNV SQIMCLLGQQ
950
951
ALEGRRVPVM VSGKTLPSFK PYETDAMAGG YVKGRFYSGI KPQEYYFHCM
1000
1001
AGREGLIDTA VKTSRSGYLQ RCLTKQLEGV HVSYDNSIRD ADGTLVQFMY
1050
1051
GGDAIDITKE SHMTQFEFCL DNYYALLKKY NPSALIEHLD VESALKYSKK
1100
1101
TLKYRKKHSK EPHYKQSVKY DPVLAKYNPA KYLGSVSENF QDKLESFLDK
1150
1151
NSKLFKSSDG VNEKKFRALM QLKYMRSLIN PGEAVGIIAS QSVGEPSTQM
1200
1201
TLNTFHFAGH GAANVTLGIP RLREIVMTAS AAIKTPQMTL PIWNDVSDEQ
1250
1251
ADTFCKSISK VLLSEVIDKV IVTETTGTSN TAGGNAARSY VIHMRFFDNN
1300
1301
EYSEEYDVSK EELQNVISNQ FIHLLEAAIV KEIKKQKRTT GPDIGVAVPR
1350
1351
LQTDVANSSS NSKRLEEDND EEQSHKKTKQ AVSYDEPDED EIETMREAEK
1400
1401
SSDEEGIDSD KESDSDSEDE DVDMNEQINK SIVEANNNMN KVQRDRQSAI
1450
1451
ISHHRFITKY NFDDESGKWC EFKLELAADT EKLLMVNIVE EICRKSIIRQ
1500
1501
IPHIDRCVHP EPENGKRVLV TEGVNFQAMW DQEAFIDVDG ITSNDVAAVL
1550
1551
KTYGVEAARN TIVNEINNVF SRYAISVSFR HLDLIADMMT RQGTYLAFNR
1600
1601
QGMETSTSSF MKMSYETTCQ FLTKAVLDNE REQLDSPSAR IVVGKLNNVG
1650
1651
TGSFDVLAKV PNAA                                       
1664
 

Show the unformatted sequence.

Checksums:
CRC64:DF65A7AA459D5E6D
MD5:8bc25527784370ee6eec70cb9e432f54

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
RNA_pol_Rpb1_1 8 - 471 4C2M A 8 - 471 Show 3D Structure View in InterPro
P 8 - 471 Show 3D Structure View in InterPro
4C3H A 8 - 471 Show 3D Structure View in InterPro
4C3I A 8 - 471 Show 3D Structure View in InterPro
4C3J A 8 - 471 Show 3D Structure View in InterPro
4YM7 AA 8 - 471 Show 3D Structure View in InterPro
BA 8 - 471 Show 3D Structure View in InterPro
CA 8 - 471 Show 3D Structure View in InterPro
DA 8 - 471 Show 3D Structure View in InterPro
EA 8 - 471 Show 3D Structure View in InterPro
FA 8 - 471 Show 3D Structure View in InterPro
5G5L A 8 - 471 Show 3D Structure View in InterPro
5LMX A 8 - 471 Show 3D Structure View in InterPro
5M3F A 8 - 471 Show 3D Structure View in InterPro
5M3M A 8 - 471 Show 3D Structure View in InterPro
5M5W A 8 - 471 Show 3D Structure View in InterPro
5M5X A 8 - 471 Show 3D Structure View in InterPro
5M5Y A 8 - 471 Show 3D Structure View in InterPro
5M64 A 8 - 471 Show 3D Structure View in InterPro
5N5Y A 8 - 471 Show 3D Structure View in InterPro
5N5Z A 8 - 471 Show 3D Structure View in InterPro
5N60 A 8 - 471 Show 3D Structure View in InterPro
5N61 A 8 - 471 Show 3D Structure View in InterPro
5OA1 A 8 - 471 Show 3D Structure View in InterPro
5W5Y A 8 - 471 Show 3D Structure View in InterPro
5W64 A 8 - 471 Show 3D Structure View in InterPro
5W65 A 8 - 471 Show 3D Structure View in InterPro
5W66 A 8 - 471 Show 3D Structure View in InterPro
6H67 A 8 - 471 Show 3D Structure View in InterPro
6H68 A 8 - 471 Show 3D Structure View in InterPro
6HKO A 8 - 471 Show 3D Structure View in InterPro
6HLQ A 8 - 471 Show 3D Structure View in InterPro
6HLR A 8 - 471 Show 3D Structure View in InterPro
6HLS A 8 - 471 Show 3D Structure View in InterPro
6RQH A 8 - 471 Show 3D Structure View in InterPro
6RQL A 8 - 471 Show 3D Structure View in InterPro
6RQT A 8 - 471 Show 3D Structure View in InterPro
6RRD A 8 - 471 Show 3D Structure View in InterPro
6RUI A 8 - 471 Show 3D Structure View in InterPro
6RUO A 8 - 471 Show 3D Structure View in InterPro
6RWE A 8 - 471 Show 3D Structure View in InterPro
6TPS A 8 - 471 Show 3D Structure View in InterPro
RNA_pol_Rpb1_2 473 - 653 4C2M A 473 - 653 Show 3D Structure View in InterPro
P 473 - 653 Show 3D Structure View in InterPro
4C3H A 473 - 653 Show 3D Structure View in InterPro
4C3I A 473 - 653 Show 3D Structure View in InterPro
4C3J A 473 - 653 Show 3D Structure View in InterPro
4YM7 AA 473 - 653 Show 3D Structure View in InterPro
BA 473 - 653 Show 3D Structure View in InterPro
CA 473 - 653 Show 3D Structure View in InterPro
DA 473 - 653 Show 3D Structure View in InterPro
EA 473 - 653 Show 3D Structure View in InterPro
FA 473 - 653 Show 3D Structure View in InterPro
5G5L A 473 - 653 Show 3D Structure View in InterPro
5M3F A 473 - 653 Show 3D Structure View in InterPro
5M3M A 473 - 653 Show 3D Structure View in InterPro
5M5W A 473 - 653 Show 3D Structure View in InterPro
5M5X A 473 - 653 Show 3D Structure View in InterPro
5M5Y A 473 - 653 Show 3D Structure View in InterPro
5M64 A 473 - 653 Show 3D Structure View in InterPro
5N5Y A 473 - 653 Show 3D Structure View in InterPro
5N5Z A 473 - 653 Show 3D Structure View in InterPro
5N60 A 473 - 653 Show 3D Structure View in InterPro
5N61 A 473 - 653 Show 3D Structure View in InterPro
5OA1 A 473 - 653 Show 3D Structure View in InterPro
5W5Y A 473 - 653 Show 3D Structure View in InterPro
5W64 A 473 - 653 Show 3D Structure View in InterPro
5W65 A 473 - 653 Show 3D Structure View in InterPro
5W66 A 473 - 653 Show 3D Structure View in InterPro
6H67 A 473 - 653 Show 3D Structure View in InterPro
6H68 A 473 - 653 Show 3D Structure View in InterPro
6HKO A 473 - 653 Show 3D Structure View in InterPro
6HLQ A 473 - 653 Show 3D Structure View in InterPro
6HLR A 473 - 653 Show 3D Structure View in InterPro
6HLS A 473 - 653 Show 3D Structure View in InterPro
6RQH A 473 - 653 Show 3D Structure View in InterPro
6RQL A 473 - 653 Show 3D Structure View in InterPro
6RQT A 473 - 653 Show 3D Structure View in InterPro
6RRD A 473 - 653 Show 3D Structure View in InterPro
6RUI A 473 - 653 Show 3D Structure View in InterPro
6RUO A 473 - 653 Show 3D Structure View in InterPro
6RWE A 473 - 653 Show 3D Structure View in InterPro
6TPS A 473 - 653 Show 3D Structure View in InterPro
474 - 653 5LMX A 474 - 653 Show 3D Structure View in InterPro
RNA_pol_Rpb1_3 656 - 833 4C2M A 656 - 833 Show 3D Structure View in InterPro
P 656 - 833 Show 3D Structure View in InterPro
4C3H A 656 - 833 Show 3D Structure View in InterPro
4C3I A 656 - 833 Show 3D Structure View in InterPro
4C3J A 656 - 833 Show 3D Structure View in InterPro
4YM7 AA 656 - 833 Show 3D Structure View in InterPro
BA 656 - 833 Show 3D Structure View in InterPro
CA 656 - 833 Show 3D Structure View in InterPro
DA 656 - 833 Show 3D Structure View in InterPro
EA 656 - 833 Show 3D Structure View in InterPro
FA 656 - 833 Show 3D Structure View in InterPro
5G5L A 656 - 833 Show 3D Structure View in InterPro
5LMX A 656 - 833 Show 3D Structure View in InterPro
5M3F A 656 - 833 Show 3D Structure View in InterPro
5M3M A 656 - 833 Show 3D Structure View in InterPro
5M5W A 656 - 833 Show 3D Structure View in InterPro
5M5X A 656 - 833 Show 3D Structure View in InterPro
5M5Y A 656 - 833 Show 3D Structure View in InterPro
5M64 A 656 - 833 Show 3D Structure View in InterPro
5N5Y A 656 - 833 Show 3D Structure View in InterPro
5N5Z A 656 - 833 Show 3D Structure View in InterPro
5N60 A 656 - 833 Show 3D Structure View in InterPro
5N61 A 656 - 833 Show 3D Structure View in InterPro
5OA1 A 656 - 833 Show 3D Structure View in InterPro
5W5Y A 656 - 833 Show 3D Structure View in InterPro
5W64 A 656 - 833 Show 3D Structure View in InterPro
5W65 A 656 - 833 Show 3D Structure View in InterPro
5W66 A 656 - 833 Show 3D Structure View in InterPro
6H67 A 656 - 833 Show 3D Structure View in InterPro
6H68 A 656 - 833 Show 3D Structure View in InterPro
6HKO A 656 - 833 Show 3D Structure View in InterPro
6HLQ A 656 - 833 Show 3D Structure View in InterPro
6HLR A 656 - 833 Show 3D Structure View in InterPro
6HLS A 656 - 833 Show 3D Structure View in InterPro
6RQH A 656 - 833 Show 3D Structure View in InterPro
6RQL A 656 - 833 Show 3D Structure View in InterPro
6RQT A 656 - 833 Show 3D Structure View in InterPro
6RRD A 656 - 833 Show 3D Structure View in InterPro
6RUI A 656 - 833 Show 3D Structure View in InterPro
6RUO A 656 - 833 Show 3D Structure View in InterPro
6RWE A 656 - 833 Show 3D Structure View in InterPro
6TPS A 656 - 833 Show 3D Structure View in InterPro
RNA_pol_Rpb1_4 863 - 982 4C2M A 863 - 982 Show 3D Structure View in InterPro
P 863 - 982 Show 3D Structure View in InterPro
4C3H A 863 - 982 Show 3D Structure View in InterPro
4C3I A 863 - 982 Show 3D Structure View in InterPro
4C3J A 863 - 982 Show 3D Structure View in InterPro
4YM7 AA 863 - 982 Show 3D Structure View in InterPro
BA 863 - 982 Show 3D Structure View in InterPro
CA 863 - 982 Show 3D Structure View in InterPro
DA 863 - 982 Show 3D Structure View in InterPro
EA 863 - 982 Show 3D Structure View in InterPro
FA 863 - 982 Show 3D Structure View in InterPro
5G5L A 863 - 982 Show 3D Structure View in InterPro
5LMX A 863 - 982 Show 3D Structure View in InterPro
5M3F A 863 - 982 Show 3D Structure View in InterPro
5M3M A 863 - 982 Show 3D Structure View in InterPro
5M5W A 863 - 982 Show 3D Structure View in InterPro
5M5X A 863 - 982 Show 3D Structure View in InterPro
5M5Y A 863 - 982 Show 3D Structure View in InterPro
5M64 A 863 - 982 Show 3D Structure View in InterPro
5N5Y A 863 - 982 Show 3D Structure View in InterPro
5N5Z A 863 - 982 Show 3D Structure View in InterPro
5N60 A 863 - 982 Show 3D Structure View in InterPro
5N61 A 863 - 982 Show 3D Structure View in InterPro
5OA1 A 863 - 982 Show 3D Structure View in InterPro
5W5Y A 863 - 982 Show 3D Structure View in InterPro
5W64 A 863 - 982 Show 3D Structure View in InterPro
5W65 A 863 - 982 Show 3D Structure View in InterPro
5W66 A 863 - 982 Show 3D Structure View in InterPro
6H67 A 863 - 982 Show 3D Structure View in InterPro
6H68 A 863 - 982 Show 3D Structure View in InterPro
6HKO A 863 - 982 Show 3D Structure View in InterPro
6HLQ A 863 - 982 Show 3D Structure View in InterPro
6HLR A 863 - 982 Show 3D Structure View in InterPro
6HLS A 863 - 982 Show 3D Structure View in InterPro
6RQH A 863 - 982 Show 3D Structure View in InterPro
6RQL A 863 - 982 Show 3D Structure View in InterPro
6RQT A 863 - 982 Show 3D Structure View in InterPro
6RRD A 863 - 982 Show 3D Structure View in InterPro
6RUI A 863 - 982 Show 3D Structure View in InterPro
6RUO A 863 - 982 Show 3D Structure View in InterPro
6RWE A 863 - 982 Show 3D Structure View in InterPro
6TPS A 863 - 982 Show 3D Structure View in InterPro
RNA_pol_Rpb1_5 989 - 1611 4C2M A 989 - 1611 Show 3D Structure View in InterPro
P 989 - 1611 Show 3D Structure View in InterPro
4C3H A 989 - 1611 Show 3D Structure View in InterPro
4C3I A 989 - 1611 Show 3D Structure View in InterPro
4C3J A 989 - 1611 Show 3D Structure View in InterPro
4YM7 AA 989 - 1611 Show 3D Structure View in InterPro
BA 989 - 1611 Show 3D Structure View in InterPro
CA 989 - 1611 Show 3D Structure View in InterPro
DA 989 - 1611 Show 3D Structure View in InterPro
EA 989 - 1611 Show 3D Structure View in InterPro
FA 989 - 1611 Show 3D Structure View in InterPro
5G5L A 989 - 1611 Show 3D Structure View in InterPro
5LMX A 989 - 1611 Show 3D Structure View in InterPro
5M3F A 989 - 1611 Show 3D Structure View in InterPro
5M3M A 989 - 1611 Show 3D Structure View in InterPro
5M5W A 989 - 1611 Show 3D Structure View in InterPro
5M5X A 989 - 1611 Show 3D Structure View in InterPro
5M5Y A 989 - 1611 Show 3D Structure View in InterPro
5M64 A 989 - 1611 Show 3D Structure View in InterPro
5N5Y A 989 - 1611 Show 3D Structure View in InterPro
5N5Z A 989 - 1611 Show 3D Structure View in InterPro
5N60 A 989 - 1611 Show 3D Structure View in InterPro
5N61 A 989 - 1611 Show 3D Structure View in InterPro
5OA1 A 989 - 1611 Show 3D Structure View in InterPro
5W5Y A 989 - 1611 Show 3D Structure View in InterPro
5W64 A 989 - 1611 Show 3D Structure View in InterPro
5W65 A 989 - 1611 Show 3D Structure View in InterPro
5W66 A 989 - 1611 Show 3D Structure View in InterPro
6H67 A 989 - 1611 Show 3D Structure View in InterPro
6H68 A 989 - 1611 Show 3D Structure View in InterPro
6HKO A 989 - 1611 Show 3D Structure View in InterPro
6HLQ A 989 - 1611 Show 3D Structure View in InterPro
6HLR A 989 - 1611 Show 3D Structure View in InterPro
6HLS A 989 - 1611 Show 3D Structure View in InterPro
6RQH A 989 - 1611 Show 3D Structure View in InterPro
6RQL A 989 - 1611 Show 3D Structure View in InterPro
6RQT A 989 - 1611 Show 3D Structure View in InterPro
6RRD A 989 - 1611 Show 3D Structure View in InterPro
6RUI A 989 - 1611 Show 3D Structure View in InterPro
6RUO A 989 - 1611 Show 3D Structure View in InterPro
6RWE A 989 - 1611 Show 3D Structure View in InterPro
6TPS A 989 - 1611 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;