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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: AL3A1_RAT (P11883)

Summary

This is the summary of UniProt entry AL3A1_RAT (P11883).

Description: Aldehyde dehydrogenase, dimeric NADP-preferring
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 453 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Aldedh 2 428
disorder n/a 82 87
disorder n/a 92 94
disorder n/a 440 453

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P11883. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSSISDTVKR AREAFNSGKT RSLQFRIQQL EALQRMINEN LKSISGALAS
50
51
DLGKNEWTSY YEEVAHVLEE LDTTIKELPD WAEDEPVAKT RQTQQDDLYI
100
101
HSEPLGVVLV IGAWNYPFNL TIQPMVGAVA AGNAVILKPS EVSGHMADLL
150
151
ATLIPQYMDQ NLYLVVKGGV PETTELLKER FDHIMYTGST AVGKIVMAAA
200
201
AKHLTPVTLE LGGKSPCYVD KDCDLDVACR RIAWGKFMNS GQTCVAPDYI
250
251
LCDPSIQNQI VEKLKKSLKD FYGEDAKQSR DYGRIINDRH FQRVKGLIDN
300
301
QKVAHGGTWD QSSRYIAPTI LVDVDPQSPV MQEEIFGPVM PIVCVRSLEE
350
351
AIQFINQREK PLALYVFSNN EKVIKKMIAE TSSGGVTAND VIVHITVPTL
400
401
PFGGVGNSGM GAYHGKKSFE TFSHRRSCLV KSLLNEEAHK ARYPPSPAKM
450
451
PRH                                                   
453
 

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Checksums:
CRC64:15C501BAB4F9845A
MD5:9c750c8513b323c631ffb3f7030d3f7f

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Aldedh 3 - 428 1AD3 A 2 - 427 Jmol OpenAstexViewer
B 2 - 427 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.