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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DCOR_HUMAN (P11926)

Summary

This is the summary of UniProt entry DCOR_HUMAN (P11926).

Description: Ornithine decarboxylase
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 461 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Orn_DAP_Arg_deC 40 387
Pfam Orn_Arg_deC_N 45 281
disorder n/a 301 303
disorder n/a 427 429

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P11926. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNNFGNEEFD CHFLDEGFTA KDILDQKINE VSSSDDKDAF YVADLGDILK
50
51
KHLRWLKALP RVTPFYAVKC NDSKAIVKTL AATGTGFDCA SKTEIQLVQS
100
101
LGVPPERIIY ANPCKQVSQI KYAANNGVQM MTFDSEVELM KVARAHPKAK
150
151
LVLRIATDDS KAVCRLSVKF GATLRTSRLL LERAKELNID VVGVSFHVGS
200
201
GCTDPETFVQ AISDARCVFD MGAEVGFSMY LLDIGGGFPG SEDVKLKFEE
250
251
ITGVINPALD KYFPSDSGVR IIAEPGRYYV ASAFTLAVNI IAKKIVLKEQ
300
301
TGSDDEDESS EQTFMYYVND GVYGSFNCIL YDHAHVKPLL QKRPKPDEKY
350
351
YSSSIWGPTC DGLDRIVERC DLPEMHVGDW MLFENMGAYT VAAASTFNGF
400
401
QRPTIYYVMS GPAWQLMQQF QNPDFPPEVE EQDASTLPVS CAWESGMKRH
450
451
RAACASASIN V                                          
461
 

Show the unformatted sequence.

Checksums:
CRC64:8CCB88CE80E823C5
MD5:f88e8c4d2a828bb0219633ddbbfa5543

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Orn_Arg_deC_N 45 - 281 1D7K A 45 - 281 Jmol OpenAstexViewer
B 45 - 281 Jmol OpenAstexViewer
2ON3 A 45 - 281 Jmol OpenAstexViewer
B 45 - 281 Jmol OpenAstexViewer
2OO0 A 45 - 281 Jmol OpenAstexViewer
B 45 - 281 Jmol OpenAstexViewer
4ZGY A 45 - 281 Jmol OpenAstexViewer
5BWA A 45 - 281 Jmol OpenAstexViewer
Orn_DAP_Arg_deC 40 - 387 1D7K A 40 - 387 Jmol OpenAstexViewer
B 40 - 387 Jmol OpenAstexViewer
2ON3 A 40 - 387 Jmol OpenAstexViewer
B 40 - 387 Jmol OpenAstexViewer
2OO0 A 40 - 387 Jmol OpenAstexViewer
B 40 - 387 Jmol OpenAstexViewer
4ZGY A 40 - 387 Jmol OpenAstexViewer
5BWA A 40 - 387 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.