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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: SIR4_YEAST (P11978)

Summary

This is the summary of UniProt entry SIR4_YEAST (P11978).

Description: Regulatory protein SIR4
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
View Pfam proteome data.
Length: 1358 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 99
low_complexity n/a 96 113
disorder n/a 105 108
disorder n/a 112 161
disorder n/a 163 164
disorder n/a 203 210
disorder n/a 226 246
disorder n/a 252 550
low_complexity n/a 449 460
disorder n/a 552 605
disorder n/a 610 632
disorder n/a 671 697
disorder n/a 701 706
disorder n/a 709 730
disorder n/a 733 735
Pfam SIR4_SID 746 894
disorder n/a 751 756
low_complexity n/a 752 772
disorder n/a 761 773
disorder n/a 776 787
disorder n/a 832 833
disorder n/a 846 847
disorder n/a 857 858
disorder n/a 894 968
disorder n/a 1104 1105
disorder n/a 1138 1146
disorder n/a 1207 1211
disorder n/a 1225 1231
disorder n/a 1233 1250
disorder n/a 1254 1259
coiled_coil n/a 1278 1305
coiled_coil n/a 1327 1347

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P11978. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPNDNKTPNR SSTPKFTKKP VTPNDKIPER EEKSNEVKTP KIPLFTFAKS
50
51
KNYSRPSTAI HTSPHQPSDV KPTSHKQLQQ PKSSPLKKNN YNSFPHSNLE
100
101
KISNSKLLSL LRSKTSAGRI ESNNPSHDAS RSLASFEQTA FSRHAQQQTS
150
151
TFNSKPVRTI VPISTSQTNN SFLSGVKSLL SEEKIRDYSK EILGINLANE
200
201
QPVLEKPLKK GSADIGASVI SLTKDKSIRK DTVEEKKEEK LNIGKNFAHS
250
251
DSLSVPKVSA GDSGISPEES KARSPGIAKP NAIQTEVYGI NEESTNERLE
300
301
INQEKPVKLD ENSANSTVAS ALDTNGTSAT TETLTSKKIV PSPKKVAIDQ
350
351
DKITLHDEKT LAPSKHQPIT SEQKMKEDAD LKRMEILKSP HLSKSPADRP
400
401
QGRRNSRNFS TRDEETTKLA FLVEYEGQEN NYNSTSRSTE KKNDMNTSAK
450
451
NKNGENKKIG KRPPEIMSTE AHVNKVTEET TKQIQSVRID GRKVLQKVQG
500
501
ESHIDSRNNT LNVTPSKRPQ LGEIPNPMKK HKPNEGRTPN ISNGTINIQK
550
551
KLEPKEIVRD ILHTKESSNE AKKTIQNPLN KSQNTALPST HKVTQKKDIK
600
601
IGTNDLFQVE SAPKISSEID RENVKSKDEP VSKAVESKSL LNLFSNVLKA
650
651
PFIKSESKPF SSDALSKEKA NFLETIASTE KPENKTDKVS LSQPVSASKH
700
701
EYSDNFPVSL SQPSKKSFAN HTEDEQIEKK KICRGRMNTI ITHPGKMELV
750
751
YVSDSDDSSS DNDSLTDLES LSSGESNEIK VTNDLDTSAE KDQIQAGKWF
800
801
DPVLDWRKSD RELTKNILWR IADKTTYDKE TITDLIEQGI PKHSYLSGNP
850
851
LTSVTNDICS VENYETSSAF FYQQVHKKDR LQYLPLYAVS TFENTNNTEK
900
901
NDVTNKNINI GKHSQEQNSS SAKPSQIPTV SSPLGFEETK LSTTPTKSNR
950
951
RVSHSDTNSS KPKNTKENLS KSSWRQEWLA NLKLISVSLV DEFPSELSDS
1000
1001
DRQIINEKMQ LLKDIFANNL KSAISNNFRE SDIIILKGEI EDYPMSSEIK
1050
1051
IYYNELQNKP DAKKARFWSF MKTQRFVSNM GFDIQKSCEP VSISTSVKPH
1100
1101
VVEPEHMADA KIMPKDILQI TKKPLMVKNV KPSSPPDVKS LVQLSTMETK
1150
1151
TLPEKKQFDS IFNSNKAKII PGNGKHASEN ISLSFSRPAS YGYFSVGKRV
1200
1201
PIVEDRRVKQ LDDITDSNTT EILTSVDVLG THSQTGTQQS NMYTSTQKTE
1250
1251
LEIDNKDSVT ECSKDMKEDG LSFVDIVLSK AASALDEKEK QLAVANEIIR
1300
1301
SLSDEVMRNE IRITSLQGDL TFTKKCLENA RSQISEKDAK INKLMEKDFQ
1350
1351
VNKEIKPY                                              
1358
 

Show the unformatted sequence.

Checksums:
CRC64:9C698765964F094E
MD5:6052a0590a5a128aadcde0e80f343081

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
SIR4_SID 746 - 893 4IAO C 746 - 893 Jmol OpenAstexViewer
D 746 - 893 Jmol OpenAstexViewer