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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DNLI1_SCHPO (P12000)

Summary

This is the summary of UniProt entry DNLI1_SCHPO (P12000).

Description: DNA ligase 1
Source organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (NCBI taxonomy ID 284812)
Length: 768 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 15 19
disorder n/a 28 143
low_complexity n/a 104 122
low_complexity n/a 124 135
Pfam DNA_ligase_A_N 148 324
disorder n/a 335 339
disorder n/a 341 342
Pfam DNA_ligase_A_M 390 595
low_complexity n/a 551 562
Pfam DNA_ligase_A_C 620 733
disorder n/a 759 760
disorder n/a 763 768

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P12000. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRTVFSQIPR FKQVNQYIRM STRQSDISNF FISSASHKSE HVEVSQSSSD
50
51
SKNVDGRSTS EKRKVESVKL VDESKHNNHD DTGTQNVERE NNIVSEAKKQ
100
101
KTLGSSSSSS DAVSSNNDSG ASTPIPLPIK EPPLESNARN DKLKGHATFA
150
151
EMVKAFTKIE NTSKRLEIID IMGTYFFGIL RDHPSDLLAC VYLSINKLGP
200
201
DYSGLELGIG ESIIMKAIGE STGQTLQQIK LSFHKVGDLG LVAQTSRQNQ
250
251
PTMFKPAALT IPFLFDSLKK IAQMSGNQSQ NRKIGVIKRL LSSCEGAEPK
300
301
YLIRALEGKL RLQLAEKTIL VALANATAQY HADKNGEKLS QQDRIEGEQI
350
351
LRDVYCQLPS YDLIVPHLIE HGLGTLRETC KLTPGIPTKP MLAKPTKQIS
400
401
EVLNTFDQAA FTCEYKYDGE RAQVHFTEDG KFYVFSRNSE NMSVRYPDIS
450
451
VSVSKWKKPD ARSFILDCEA VGWDRDENKI LPFQKLATRK RKDVKIGDIK
500
501
VRACLFAFDI LYLNGQPLLE TPLNERRKLL YSMFQPSTGD FTFAKHSDQK
550
551
SIESIEEFLE ESVKDSCEGL MVKMLEGPDS HYEPSKRSRH WLKVKKDYLS
600
601
GVGDSLDLIV IGAYYGKGKR TSVYGAFLLG CYDPDTETVQ SICKLGTGFS
650
651
EEHLETFYNQ LKDIVISKKK DFYAHSDVPA HQPDVWFEPK YLWEVLAADL
700
701
SLSPVYKAAI GYVQEDKGIS LRFPRFIRIR EDKSWEDATT SEQVSEFYRS
750
751
QVAYSQKEKE GSPAAEDY                                   
768
 

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Checksums:
CRC64:6783FF3DDC675F31
MD5:89e48ee250d883986de0e553f8c4822f

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;