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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: CY24A_HUMAN (P13498)

Summary

This is the summary of UniProt entry CY24A_HUMAN (P13498).

Description: Cytochrome b-245 light chain
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 195 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Cytochrom_B558a 2 193
transmembrane n/a 12 30
transmembrane n/a 36 54
transmembrane n/a 75 97
transmembrane n/a 103 124
disorder n/a 134 193
low_complexity n/a 150 167
low_complexity n/a 166 182

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P13498. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGQIEWAMWA NEQALASGLI LITGGIVATA GRFTQWYFGA YSIVAGVFVC
50
51
LLEYPRGKRK KGSTMERWGQ KYMTAVVKLF GPFTRNYYVR AVLHLLLSVP
100
101
AGFLLATILG TACLAIASGI YLLAAVRGEQ WTPIEPKPRE RPQIGGTIKQ
150
151
PPSNPPPRPP AEARKKPSEE EAAVAAGGPP GGPQVNPIPV TDEVV     
195
 

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Checksums:
CRC64:428427AD19398240
MD5:e1f69e11ea9866ddce75a0dd8826be1d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Cytochrom_B558a 149 - 168 1WLP A 6 - 25 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.