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42  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TF_HUMAN (P13726)

Summary

This is the summary of UniProt entry TF_HUMAN (P13726).

Description: Tissue factor
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 295 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 8
Pfam Tissue_fac 17 118
disorder n/a 119 124
Pfam Interfer-bind 138 245
low_complexity n/a 190 203
disorder n/a 236 237
low_complexity n/a 251 271
transmembrane n/a 252 274

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P13726. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
METPAWPRVP RPETAVARTL LLGWVFAQVA GASGTTNTVA AYNLTWKSTN
50
51
FKTILEWEPK PVNQVYTVQI STKSGDWKSK CFYTTDTECD LTDEIVKDVK
100
101
QTYLARVFSY PAGNVESTGS AGEPLYENSP EFTPYLETNL GQPTIQSFEQ
150
151
VGTKVNVTVE DERTLVRRNN TFLSLRDVFG KDLIYTLYYW KSSSSGKKTA
200
201
KTNTNEFLID VDKGENYCFS VQAVIPSRTV NRKSTDSPVE CMGQEKGEFR
250
251
EIFYIIGAVV FVVIILVIIL AISLHKCRKA GVGQSWKENS PLNVS     
295
 

Show the unformatted sequence.

Checksums:
CRC64:D3486C713ED8EAD0
MD5:5a0c5594ba4c554394765516c0277628

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Interfer-bind 138 - 237 1O5D T 106 - 205 Jmol OpenAstexViewer
2B7D T 106 - 205 Jmol OpenAstexViewer
2F9B T 106 - 205 Jmol OpenAstexViewer
2FLB T 106 - 205 Jmol OpenAstexViewer
2FLR T 106 - 205 Jmol OpenAstexViewer
138 - 241 2PUQ T 106 - 209 Jmol OpenAstexViewer
3ELA T 106 - 209 Jmol OpenAstexViewer
3TH3 T 106 - 209 Jmol OpenAstexViewer
138 - 242 1DAN U 106 - 210 Jmol OpenAstexViewer
1FAK T 106 - 210 Jmol OpenAstexViewer
1J9C T 106 - 210 Jmol OpenAstexViewer
1TFH B 106 - 210 Jmol OpenAstexViewer
1UJ3 C 706 - 810 Jmol OpenAstexViewer
1W0Y T 106 - 210 Jmol OpenAstexViewer
1W2K T 106 - 210 Jmol OpenAstexViewer
1WQV T 106 - 210 Jmol OpenAstexViewer
1WSS T 106 - 210 Jmol OpenAstexViewer
1WTG T 106 - 210 Jmol OpenAstexViewer
1WUN T 106 - 210 Jmol OpenAstexViewer
1WV7 T 106 - 210 Jmol OpenAstexViewer
2A2Q T 106 - 210 Jmol OpenAstexViewer
2AER T 106 - 210 Jmol OpenAstexViewer
2B8O T 106 - 210 Jmol OpenAstexViewer
2C4F U 106 - 210 Jmol OpenAstexViewer
2EC9 U 106 - 210 Jmol OpenAstexViewer
2FIR T 106 - 210 Jmol OpenAstexViewer
2ZP0 T 106 - 210 Jmol OpenAstexViewer
2ZWL T 106 - 210 Jmol OpenAstexViewer
2ZZU T 106 - 210 Jmol OpenAstexViewer
3TH2 T 106 - 210 Jmol OpenAstexViewer
3TH4 T 106 - 210 Jmol OpenAstexViewer
4IBL T 106 - 210 Jmol OpenAstexViewer
4M7L T 106 - 210 Jmol OpenAstexViewer
4YLQ T 106 - 210 Jmol OpenAstexViewer
4Z6A T 106 - 210 Jmol OpenAstexViewer
4ZMA T 106 - 210 Jmol OpenAstexViewer
138 - 243 1AHW C 106 - 211 Jmol OpenAstexViewer
F 106 - 211 Jmol OpenAstexViewer
1JPS T 106 - 211 Jmol OpenAstexViewer
1TFH A 106 - 211 Jmol OpenAstexViewer
1Z6J T 106 - 211 Jmol OpenAstexViewer
2AEI T 106 - 211 Jmol OpenAstexViewer
2HFT A 106 - 211 Jmol OpenAstexViewer
138 - 245 1BOY A 106 - 213 Jmol OpenAstexViewer
Tissue_fac 33 - 118 1J9C T 1 - 86 Jmol OpenAstexViewer
1Z6J T 1 - 86 Jmol OpenAstexViewer
2HFT A 1 - 86 Jmol OpenAstexViewer
4YLQ T 1 - 86 Jmol OpenAstexViewer
35 - 118 1BOY A 3 - 86 Jmol OpenAstexViewer
36 - 112 4ZMA T 4 - 80 Jmol OpenAstexViewer
36 - 114 1AHW C 4 - 82 Jmol OpenAstexViewer
F 4 - 82 Jmol OpenAstexViewer
36 - 115 4Z6A T 4 - 83 Jmol OpenAstexViewer
37 - 113 2AEI T 5 - 81 Jmol OpenAstexViewer
37 - 115 1JPS T 5 - 83 Jmol OpenAstexViewer
1TFH A 5 - 83 Jmol OpenAstexViewer
B 5 - 83 Jmol OpenAstexViewer
38 - 111 1W0Y T 6 - 79 Jmol OpenAstexViewer
1W2K T 6 - 79 Jmol OpenAstexViewer
1WQV T 6 - 79 Jmol OpenAstexViewer
1WSS T 6 - 79 Jmol OpenAstexViewer
1WTG T 6 - 79 Jmol OpenAstexViewer
1WUN T 6 - 79 Jmol OpenAstexViewer
1WV7 T 6 - 79 Jmol OpenAstexViewer
2ZP0 T 6 - 79 Jmol OpenAstexViewer
2ZWL T 6 - 79 Jmol OpenAstexViewer
2ZZU T 6 - 79 Jmol OpenAstexViewer
38 - 112 1DAN T 6 - 80 Jmol OpenAstexViewer
1FAK T 6 - 80 Jmol OpenAstexViewer
2C4F T 6 - 80 Jmol OpenAstexViewer
2EC9 T 6 - 80 Jmol OpenAstexViewer
4M7L T 6 - 80 Jmol OpenAstexViewer
38 - 114 2A2Q T 6 - 82 Jmol OpenAstexViewer
2AER T 6 - 82 Jmol OpenAstexViewer
2B8O T 6 - 82 Jmol OpenAstexViewer
2FIR T 6 - 82 Jmol OpenAstexViewer
3TH2 T 6 - 82 Jmol OpenAstexViewer
3TH3 T 6 - 82 Jmol OpenAstexViewer
3TH4 T 6 - 82 Jmol OpenAstexViewer
4IBL T 6 - 82 Jmol OpenAstexViewer
38 - 118 1O5D T 6 - 86 Jmol OpenAstexViewer
1UJ3 C 606 - 686 Jmol OpenAstexViewer
2B7D T 6 - 86 Jmol OpenAstexViewer
2F9B T 6 - 86 Jmol OpenAstexViewer
2FLB T 6 - 86 Jmol OpenAstexViewer
2FLR T 6 - 86 Jmol OpenAstexViewer
2PUQ T 6 - 86 Jmol OpenAstexViewer
3ELA T 6 - 86 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.