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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ELAS_PSEAE (P14756)

Summary

This is the summary of UniProt entry ELAS_PSEAE (P14756).

Description: Elastase EC=3.4.24.26
Source organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (NCBI taxonomy ID 208964)
Length: 498 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 23
Pfam FTP 56 101
Pfam PepSY 122 192
disorder n/a 134 137
disorder n/a 195 197
Pfam Peptidase_M4 207 345
disorder n/a 238 240
Pfam Peptidase_M4_C 348 492

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P14756. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKKVSTLDLL FVAIMGVSPA AFAADLIDVS KLPSKAAQGA PGPVTLQAAV
50
51
GAGGADELKA IRSTTLPNGK QVTRYEQFHN GVRVVGEAIT EVKGPGKSVA
100
101
AQRSGHFVAN IAADLPGSTT AAVSAEQVLA QAKSLKAQGR KTENDKVELV
150
151
IRLGENNIAQ LVYNVSYLIP GEGLSRPHFV IDAKTGEVLD QWEGLAHAEA
200
201
GGPGGNQKIG KYTYGSDYGP LIVNDRCEMD DGNVITVDMN SSTDDSKTTP
250
251
FRFACPTNTY KQVNGAYSPL NDAHFFGGVV FKLYRDWFGT SPLTHKLYMK
300
301
VHYGRSVENA YWDGTAMLFG DGATMFYPLV SLDVAAHEVS HGFTEQNSGL
350
351
IYRGQSGGMN EAFSDMAGEA AEFYMRGKND FLIGYDIKKG SGALRYMDQP
400
401
SRDGRSIDNA SQYYNGIDVH HSSGVYNRAF YLLANSPGWD TRKAFEVFVD
450
451
ANRYYWTATS NYNSGACGVI RSAQNRNYSA ADVTRAFSTV GVTCPSAL  
498
 

Show the unformatted sequence.

Checksums:
CRC64:4B6AA96A569D9615
MD5:435e42b9578de1067aa7acde72e91a4d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Peptidase_M4 207 - 345 1EZM A 10 - 148 Show 3D Structure View in InterPro
1U4G A 10 - 148 Show 3D Structure View in InterPro
3DBK A 10 - 148 Show 3D Structure View in InterPro
6F8B A 10 - 148 Show 3D Structure View in InterPro
6FZX A 10 - 148 Show 3D Structure View in InterPro
Peptidase_M4_C 348 - 492 1EZM A 151 - 295 Show 3D Structure View in InterPro
1U4G A 151 - 295 Show 3D Structure View in InterPro
3DBK A 151 - 295 Show 3D Structure View in InterPro
6F8B A 151 - 295 Show 3D Structure View in InterPro
6FZX A 151 - 295 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;